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A genome-wide association study with 1,126,563 individuals identifies new risk loci for Alzheimer's disease.
Wightman DP, Jansen IE, Savage JE, Shadrin AA, Bahrami S, Holland D, Rongve A, Børte S, Winsvold BS, Drange OK, Martinsen AE, Skogholt AH, Willer C, Bråthen G, Bosnes I, Nielsen JB, Fritsche LG, Thomas LF, Pedersen LM, Gabrielsen ME, Johnsen MB, Meisingset TW, Zhou W, Proitsi P, Hodges A, Dobson R, Velayudhan L, Heilbron K, Auton A; 23andMe Research Team; Sealock JM, Davis LK, Pedersen NL, Reynolds CA, Karlsson IK, Magnusson S, Stefansson H, Thordardottir S, Jonsson PV, Snaedal J, Zettergren A, Skoog I, Kern S, Waern M, Zetterberg H, Blennow K, Stordal E, Hveem K, Zwart JA, Athanasiu L, Selnes P, Saltvedt I, Sando SB, Ulstein I, Djurovic S, Fladby T, Aarsland D, Selbæk G, Ripke S, Stefansson K, Andreassen OA, Posthuma D. Wightman DP, et al. Among authors: velayudhan l. Nat Genet. 2021 Sep;53(9):1276-1282. doi: 10.1038/s41588-021-00921-z. Epub 2021 Sep 7. Nat Genet. 2021. PMID: 34493870 Free PMC article.
Entorhinal cortex thickness predicts cognitive decline in Alzheimer's disease.
Velayudhan L, Proitsi P, Westman E, Muehlboeck JS, Mecocci P, Vellas B, Tsolaki M, Kłoszewska I, Soininen H, Spenger C, Hodges A, Powell J, Lovestone S, Simmons A; dNeuroMed Consortium. Velayudhan L, et al. J Alzheimers Dis. 2013;33(3):755-66. doi: 10.3233/JAD-2012-121408. J Alzheimers Dis. 2013. PMID: 23047370
Alleles that increase risk for type 2 diabetes mellitus are not associated with increased risk for Alzheimer's disease.
Proitsi P, Lupton MK, Velayudhan L, Hunter G, Newhouse S, Lin K, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Craig D, Todd S, Johnston JA, McGuinness B, Kloszewska I, Soininen H, Mecocci P, Vellas B, Passmore PA, Sims R, Williams J, Brayne C; Alzheimer's Disease Neuroimaging Initiative; GERAD1 Consortium; Stewart R, Sham P, Lovestone S, Powell JF. Proitsi P, et al. Among authors: velayudhan l. Neurobiol Aging. 2014 Dec;35(12):2883.e3-2883.e10. doi: 10.1016/j.neurobiolaging.2014.07.023. Epub 2014 Jul 24. Neurobiol Aging. 2014. PMID: 25150574
Genetic predisposition to increased blood cholesterol and triglyceride lipid levels and risk of Alzheimer disease: a Mendelian randomization analysis.
Proitsi P, Lupton MK, Velayudhan L, Newhouse S, Fogh I, Tsolaki M, Daniilidou M, Pritchard M, Kloszewska I, Soininen H, Mecocci P, Vellas B; Alzheimer's Disease Neuroimaging Initiative; Williams J; GERAD1 Consortium; Stewart R, Sham P, Lovestone S, Powell JF. Proitsi P, et al. Among authors: velayudhan l. PLoS Med. 2014 Sep 16;11(9):e1001713. doi: 10.1371/journal.pmed.1001713. eCollection 2014 Sep. PLoS Med. 2014. PMID: 25226301 Free PMC article.
Association of blood lipids with Alzheimer's disease: A comprehensive lipidomics analysis.
Proitsi P, Kim M, Whiley L, Simmons A, Sattlecker M, Velayudhan L, Lupton MK, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Lovestone S, Powell JF, Dobson RJ, Legido-Quigley C. Proitsi P, et al. Among authors: velayudhan l. Alzheimers Dement. 2017 Feb;13(2):140-151. doi: 10.1016/j.jalz.2016.08.003. Epub 2016 Sep 28. Alzheimers Dement. 2017. PMID: 27693183 Free article.
Association between Plasma Ceramides and Phosphatidylcholines and Hippocampal Brain Volume in Late Onset Alzheimer's Disease.
Kim M, Nevado-Holgado A, Whiley L, Snowden SG, Soininen H, Kloszewska I, Mecocci P, Tsolaki M, Vellas B, Thambisetty M, Dobson RJB, Powell JF, Lupton MK, Simmons A, Velayudhan L, Lovestone S, Proitsi P, Legido-Quigley C. Kim M, et al. Among authors: velayudhan l. J Alzheimers Dis. 2017;60(3):809-817. doi: 10.3233/JAD-160645. J Alzheimers Dis. 2017. PMID: 27911300 Free PMC article.
New Therapeutic Strategies for Lewy Body Dementias.
Velayudhan L, Ffytche D, Ballard C, Aarsland D. Velayudhan L, et al. Curr Neurol Neurosci Rep. 2017 Sep;17(9):68. doi: 10.1007/s11910-017-0778-2. Curr Neurol Neurosci Rep. 2017. PMID: 28741230 Review.
75 results