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Novel lectin-based chimeric antigen receptors target Gb3-positive tumour cells.
Meléndez AV, Velasco Cárdenas RM, Lagies S, Strietz J, Siukstaite L, Thomas OS, Tomisch J, Weber W, Kammerer B, Römer W, Minguet S. Meléndez AV, et al. Among authors: velasco cardenas rm. Cell Mol Life Sci. 2022 Sep 12;79(10):513. doi: 10.1007/s00018-022-04524-7. Cell Mol Life Sci. 2022. PMID: 36097202 Free PMC article.
Harnessing CD3 diversity to optimize CAR T cells.
Velasco Cárdenas RM, Brandl SM, Meléndez AV, Schlaak AE, Buschky A, Peters T, Beier F, Serrels B, Taromi S, Raute K, Hauri S, Gstaiger M, Lassmann S, Huppa JB, Boerries M, Andrieux G, Bengsch B, Schamel WW, Minguet S. Velasco Cárdenas RM, et al. Nat Immunol. 2023 Dec;24(12):2135-2149. doi: 10.1038/s41590-023-01658-z. Epub 2023 Nov 6. Nat Immunol. 2023. PMID: 37932456 Free PMC article.
Rational design of a trimeric APRIL-based CAR-binding domain enables efficient targeting of multiple myeloma.
Schmidts A, Ormhøj M, Choi BD, Taylor AO, Bouffard AA, Scarfò I, Larson RC, Frigault MJ, Gallagher K, Castano AP, Riley LS, Cabral ML, Boroughs AC, Velasco Cárdenas RM, Schamel W, Zhou J, Mackay S, Tai YT, Anderson KC, Maus MV. Schmidts A, et al. Among authors: velasco cardenas rm. Blood Adv. 2019 Nov 12;3(21):3248-3260. doi: 10.1182/bloodadvances.2019000703. Blood Adv. 2019. PMID: 31698455 Free PMC article.
Kidins220 and Aiolos promote thymic iNKT cell development by reducing TCR signals.
Herr LA, Fiala GJ, Sagar, Schaffer AM, Hummel JF, Zintchenko M, Raute K, Velasco Cárdenas RM, Heizmann B, Ebert K, Fehrenbach K, Janowska I, Chan S, Tanriver Y, Minguet S, Schamel WW. Herr LA, et al. Among authors: velasco cardenas rm. Sci Adv. 2024 Mar 15;10(11):eadj2802. doi: 10.1126/sciadv.adj2802. Epub 2024 Mar 15. Sci Adv. 2024. PMID: 38489359 Free PMC article.
Association of the polymorphisms rs179008 (TLR7), rs2004640 (IRF5), rs1800795 (IL-6) and rs2280788 (CCL5) with systemic lupus erythematosus in women of Mayan ethnicity from Yucatan.
Nakazawa-Ueji YE, Valencia-Pacheco G, González-Herrera LJ, Chan-Chalé L, Velasco-Cárdenas RM, Carreño-Gonzalez MJ, Pérez-Mendoza G, Amaro-Adrián GI, Rodríguez-Dzul EA, Quintal-Ortiz IG, Angulo-Ramírez AV, López-Villanueva RF. Nakazawa-Ueji YE, et al. Among authors: velasco cardenas rm. Nucleosides Nucleotides Nucleic Acids. 2024 Mar 8:1-17. doi: 10.1080/15257770.2024.2325438. Online ahead of print. Nucleosides Nucleotides Nucleic Acids. 2024. PMID: 38459707
Loss of Neurological Disease HSAN-I-Associated Gene SPTLC2 Impairs CD8+ T Cell Responses to Infection by Inhibiting T Cell Metabolic Fitness.
Wu J, Ma S, Sandhoff R, Ming Y, Hotz-Wagenblatt A, Timmerman V, Bonello-Palot N, Schlotter-Weigel B, Auer-Grumbach M, Seeman P, Löscher WN, Reindl M, Weiss F, Mah E, Weisshaar N, Madi A, Mohr K, Schlimbach T, Velasco Cárdenas RM, Koeppel J, Grünschläger F, Müller L, Baumeister M, Brügger B, Schmitt M, Wabnitz G, Samstag Y, Cui G. Wu J, et al. Among authors: velasco cardenas rm. Immunity. 2019 May 21;50(5):1218-1231.e5. doi: 10.1016/j.immuni.2019.03.005. Epub 2019 Apr 2. Immunity. 2019. PMID: 30952607 Free PMC article.
Expression of TLR-7, MyD88, NF-kB, and INF-α in B Lymphocytes of Mayan Women with Systemic Lupus Erythematosus in Mexico.
Pacheco GV, Novelo Noh IB, Velasco Cárdenas RM, Angulo Ramírez AV, López Villanueva RF, Quintal Ortiz IG, Alonso Salomón LG, Ruz NP, Rivero Cárdenas NA. Pacheco GV, et al. Among authors: velasco cardenas rm. Front Immunol. 2016 Feb 2;7:22. doi: 10.3389/fimmu.2016.00022. eCollection 2016. Front Immunol. 2016. PMID: 26870038 Free PMC article.