Vekrellis K - Search Results

1

Modeling alpha-synuclein pathology in a human brain-chip to assess blood-brain barrier disruption.

Pediaditakis I, Kodella KR, Manatakis DV, Le CY, Hinojosa CD, Tien-Street W, Manolakos ES, Vekrellis K, Hamilton GA, Ewart L, Rubin LL, Karalis K. Pediaditakis I, et al. Among authors: vekrellis k. Nat Commun. 2021 Oct 8;12(1):5907. doi: 10.1038/s41467-021-26066-5. Nat Commun. 2021. PMID: 34625559 Free PMC article.

2

alpha-synuclein degradation by autophagic pathways: a potential key to Parkinson's disease pathogenesis.

Xilouri M, Vogiatzi T, Vekrellis K, Stefanis L. Xilouri M, et al. Among authors: vekrellis k. Autophagy. 2008 Oct;4(7):917-9. doi: 10.4161/auto.6685. Epub 2008 Oct 26. Autophagy. 2008. PMID: 18708765

3

Abberant alpha-synuclein confers toxicity to neurons in part through inhibition of chaperone-mediated autophagy.

Xilouri M, Vogiatzi T, Vekrellis K, Park D, Stefanis L. Xilouri M, et al. Among authors: vekrellis k. PLoS One. 2009;4(5):e5515. doi: 10.1371/journal.pone.0005515. Epub 2009 May 13. PLoS One. 2009. PMID: 19436756 Free PMC article.

4

Assessment of α-synuclein secretion in mouse and human brain parenchyma.

Emmanouilidou E, Elenis D, Papasilekas T, Stranjalis G, Gerozissis K, Ioannou PC, Vekrellis K. Emmanouilidou E, et al. Among authors: vekrellis k. PLoS One. 2011;6(7):e22225. doi: 10.1371/journal.pone.0022225. Epub 2011 Jul 14. PLoS One. 2011. PMID: 21779395 Free PMC article.

5

Pathological roles of α-synuclein in neurological disorders.

Vekrellis K, Xilouri M, Emmanouilidou E, Rideout HJ, Stefanis L. Vekrellis K, et al. Lancet Neurol. 2011 Nov;10(11):1015-25. doi: 10.1016/S1474-4422(11)70213-7. Lancet Neurol. 2011. PMID: 22014436 Review.

6

Targeting intracellular and extracellular alpha-synuclein as a therapeutic strategy in Parkinson's disease and other synucleinopathies.

Vekrellis K, Stefanis L. Vekrellis K, et al. Expert Opin Ther Targets. 2012 Apr;16(4):421-32. doi: 10.1517/14728222.2012.674111. Expert Opin Ther Targets. 2012. PMID: 22480256 Review.

7

In silico modeling of the effects of alpha-synuclein oligomerization on dopaminergic neuronal homeostasis.

Ouzounoglou E, Kalamatianos D, Emmanouilidou E, Xilouri M, Stefanis L, Vekrellis K, Manolakos ES. Ouzounoglou E, et al. Among authors: vekrellis k. BMC Syst Biol. 2014 May 13;8:54. doi: 10.1186/1752-0509-8-54. BMC Syst Biol. 2014. PMID: 24885905 Free PMC article.

8

Exocytosis and Spreading of Normal and Aberrant α-Synuclein.

Emmanouilidou E, Vekrellis K. Emmanouilidou E, et al. Among authors: vekrellis k. Brain Pathol. 2016 May;26(3):398-403. doi: 10.1111/bpa.12373. Brain Pathol. 2016. PMID: 26940375 Free PMC article. Review.

9

How is alpha-synuclein cleared from the cell?

Stefanis L, Emmanouilidou E, Pantazopoulou M, Kirik D, Vekrellis K, Tofaris GK. Stefanis L, et al. Among authors: vekrellis k. J Neurochem. 2019 Sep;150(5):577-590. doi: 10.1111/jnc.14704. Epub 2019 May 8. J Neurochem. 2019. PMID: 31069800 Free article. Review.

10

Elevated Serum α-Synuclein Levels in Huntington's Disease Patients.

Breza M, Emmanouilidou E, Leandrou E, Kartanou C, Bougea A, Panas M, Stefanis L, Karadima G, Vekrellis K, Koutsis G. Breza M, et al. Among authors: vekrellis k. Neuroscience. 2020 Apr 1;431:34-39. doi: 10.1016/j.neuroscience.2020.01.037. Epub 2020 Feb 8. Neuroscience. 2020. PMID: 32045629

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