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Repurposing Study of 4-Acyl-1-phenylaminocarbonyl-2-substituted-piperazine Derivatives as Potential Anticancer Agents-In Vitro Evaluation against Breast Cancer Cells.
Guillén-Mancina E, García-Lozano MDR, Burgos-Morón E, Mazzotta S, Martínez-Aguado P, Calderón-Montaño JM, Vega-Pérez JM, López-Lázaro M, Iglesias-Guerra F, Vega-Holm M. Guillén-Mancina E, et al. Among authors: vega perez jm. Int J Mol Sci. 2023 Dec 1;24(23):17041. doi: 10.3390/ijms242317041. Int J Mol Sci. 2023. PMID: 38069364 Free PMC article.
New 4-Acyl-1-phenylaminocarbonyl-2-phenylpiperazine Derivatives as Potential Inhibitors of Adenovirus Infection. Synthesis, Biological Evaluation, and Structure-activity Relationships.
Sánchez-Céspedes J, Martínez-Aguado P, Vega-Holm M, Serna-Gallego A, Candela JI, Marrugal-Lorenzo JA, Pachón J, Iglesias-Guerra F, Vega-Pérez JM. Sánchez-Céspedes J, et al. Among authors: vega perez jm. J Med Chem. 2016 Jun 9;59(11):5432-48. doi: 10.1021/acs.jmedchem.6b00300. Epub 2016 May 31. J Med Chem. 2016. PMID: 27195951
Selective cytotoxic activity and DNA damage by an epoxyalkyl galactopyranoside.
Burgos-Morón E, Pastor N, Orta ML, Jiménez-Alonso JJ, Vega-Holm M, Vega-Pérez JM, Iglesias-Guerra F, Mateos S, López-Lázaro M, Calderón-Montaño JM. Burgos-Morón E, et al. Among authors: vega perez jm. Drug Dev Res. 2018 Dec;79(8):426-436. doi: 10.1002/ddr.21483. Epub 2018 Oct 30. Drug Dev Res. 2018. PMID: 30375672
Optimization of piperazine-derived ureas privileged structures for effective antiadenovirus agents.
Mazzotta S, Marrugal-Lorenzo JA, Vega-Holm M, Serna-Gallego A, Álvarez-Vidal J, Berastegui-Cabrera J, Pérez Del Palacio J, Díaz C, Aiello F, Pachón J, Iglesias-Guerra F, Vega-Pérez JM, Sánchez-Céspedes J. Mazzotta S, et al. Among authors: vega perez jm. Eur J Med Chem. 2020 Jan 1;185:111840. doi: 10.1016/j.ejmech.2019.111840. Epub 2019 Nov 3. Eur J Med Chem. 2020. PMID: 31711794
Exploration of piperazine-derived thioureas as antibacterial and anti-inflammatory agents. In vitro evaluation against clinical isolates of colistin-resistant Acinetobacter baumannii.
Mazzotta S, Cebrero-Cangueiro T, Frattaruolo L, Vega-Holm M, Carretero-Ledesma M, Sánchez-Céspedes J, Cappello AR, Aiello F, Pachón J, Vega-Pérez JM, Iglesias-Guerra F, Pachón-Ibáñez ME. Mazzotta S, et al. Among authors: vega perez jm. Bioorg Med Chem Lett. 2020 Sep 15;30(18):127411. doi: 10.1016/j.bmcl.2020.127411. Epub 2020 Jul 15. Bioorg Med Chem Lett. 2020. PMID: 32717617
Serinol-Based Benzoic Acid Esters as New Scaffolds for the Development of Adenovirus Infection Inhibitors: Design, Synthesis, and In Vitro Biological Evaluation.
Mazzotta S, Berastegui-Cabrera J, Carullo G, Vega-Holm M, Carretero-Ledesma M, Mendolia L, Aiello F, Iglesias-Guerra F, Pachón J, Vega-Pérez JM, Sánchez-Céspedes J. Mazzotta S, et al. Among authors: vega perez jm. ACS Infect Dis. 2021 Jun 11;7(6):1433-1444. doi: 10.1021/acsinfecdis.0c00515. Epub 2020 Oct 19. ACS Infect Dis. 2021. PMID: 33073569
Design, synthesis and in vitro biological evaluation of a novel class of anti-adenovirus agents based on 3-amino-1,2-propanediol.
Mazzotta S, Berastegui-Cabrera J, Vega-Holm M, García-Lozano MDR, Carretero-Ledesma M, Aiello F, Vega-Pérez JM, Pachón J, Iglesias-Guerra F, Sánchez-Céspedes J. Mazzotta S, et al. Among authors: vega perez jm. Bioorg Chem. 2021 Sep;114:105095. doi: 10.1016/j.bioorg.2021.105095. Epub 2021 Jun 13. Bioorg Chem. 2021. PMID: 34175724 Free article.
In Vitro Anticancer Activity and Mechanism of Action of an Aziridinyl Galactopyranoside.
Burgos-Morón E, Pastor N, Orta ML, Jiménez-Alonso JJ, Palo-Nieto C, Vega-Holm M, Vega-Pérez JM, Iglesias-Guerra F, Mateos S, López-Lázaro M, Calderón-Montaño JM. Burgos-Morón E, et al. Among authors: vega perez jm. Biomedicines. 2021 Dec 25;10(1):41. doi: 10.3390/biomedicines10010041. Biomedicines. 2021. PMID: 35052721 Free PMC article.
16 results