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Therapeutic administration of a cross-reactive mAb targeting the fusion glycoprotein of Nipah virus protects nonhuman primates.
Zeitlin L, Cross RW, Woolsey C, West BR, Borisevich V, Agans KN, Prasad AN, Deer DJ, Stuart L, McCavitt-Malvido M, Kim DH, Pettitt J, Crowe JE Jr, Whaley KJ, Veesler D, Dimitrov A, Abelson DM, Geisbert TW, Broder CC. Zeitlin L, et al. Among authors: veesler d. Sci Transl Med. 2024 Apr 3;16(741):eadl2055. doi: 10.1126/scitranslmed.adl2055. Epub 2024 Apr 3. Sci Transl Med. 2024. PMID: 38569014
An antibody against the F glycoprotein inhibits Nipah and Hendra virus infections.
Dang HV, Chan YP, Park YJ, Snijder J, Da Silva SC, Vu B, Yan L, Feng YR, Rockx B, Geisbert TW, Mire CE, Broder CC, Veesler D. Dang HV, et al. Among authors: veesler d. Nat Struct Mol Biol. 2019 Oct;26(10):980-987. doi: 10.1038/s41594-019-0308-9. Epub 2019 Sep 30. Nat Struct Mol Biol. 2019. PMID: 31570878 Free PMC article.
Broadly neutralizing antibody cocktails targeting Nipah virus and Hendra virus fusion glycoproteins.
Dang HV, Cross RW, Borisevich V, Bornholdt ZA, West BR, Chan YP, Mire CE, Da Silva SC, Dimitrov AS, Yan L, Amaya M, Navaratnarajah CK, Zeitlin L, Geisbert TW, Broder CC, Veesler D. Dang HV, et al. Among authors: veesler d. Nat Struct Mol Biol. 2021 May;28(5):426-434. doi: 10.1038/s41594-021-00584-8. Epub 2021 Apr 29. Nat Struct Mol Biol. 2021. PMID: 33927387
Architecture and antigenicity of the Nipah virus attachment glycoprotein.
Wang Z, Amaya M, Addetia A, Dang HV, Reggiano G, Yan L, Hickey AC, DiMaio F, Broder CC, Veesler D. Wang Z, et al. Among authors: veesler d. Science. 2022 Mar 25;375(6587):1373-1378. doi: 10.1126/science.abm5561. Epub 2022 Mar 3. Science. 2022. PMID: 35239409
Structure and design of Langya virus glycoprotein antigens.
Wang Z, McCallum M, Yan L, Sharkey W, Park YJ, Dang HV, Amaya M, Person A, Broder CC, Veesler D. Wang Z, et al. Among authors: veesler d. bioRxiv [Preprint]. 2023 Aug 26:2023.08.20.554025. doi: 10.1101/2023.08.20.554025. bioRxiv. 2023. PMID: 37645760 Free PMC article. Updated. Preprint.
Potent monoclonal antibody-mediated neutralization of a divergent Hendra virus variant.
Wang Z, Dang HV, Amaya M, Xu Y, Yin R, Yan L, Hickey AC, Annand EJ, Horsburgh BA, Reid PA, Smith I, Eden JS, Xu K, Broder CC, Veesler D. Wang Z, et al. Among authors: veesler d. Proc Natl Acad Sci U S A. 2022 May 31;119(22):e2122769119. doi: 10.1073/pnas.2122769119. Epub 2022 May 26. Proc Natl Acad Sci U S A. 2022. PMID: 35617431 Free PMC article.
An Alphavirus-derived replicon RNA vaccine induces SARS-CoV-2 neutralizing antibody and T cell responses in mice and nonhuman primates.
Erasmus JH, Khandhar AP, O'Connor MA, Walls AC, Hemann EA, Murapa P, Archer J, Leventhal S, Fuller JT, Lewis TB, Draves KE, Randall S, Guerriero KA, Duthie MS, Carter D, Reed SG, Hawman DW, Feldmann H, Gale M Jr, Veesler D, Berglund P, Fuller DH. Erasmus JH, et al. Among authors: veesler d. Sci Transl Med. 2020 Aug 5;12(555):eabc9396. doi: 10.1126/scitranslmed.abc9396. Epub 2020 Jul 20. Sci Transl Med. 2020. PMID: 32690628 Free PMC article.
Durable protection against the SARS-CoV-2 Omicron variant is induced by an adjuvanted subunit vaccine.
Arunachalam PS, Feng Y, Ashraf U, Hu M, Walls AC, Edara VV, Zarnitsyna VI, Aye PP, Golden N, Miranda MC, Green KWM, Threeton BM, Maness NJ, Beddingfield BJ, Bohm RP, Scheuermann SE, Goff K, Dufour J, Russell-Lodrigue K, Kepl E, Fiala B, Wrenn S, Ravichandran R, Ellis D, Carter L, Rogers K, Shirreff LM, Ferrell DE, Deb Adhikary NR, Fontenot J, Hammond HL, Frieman M, Grifoni A, Sette A, O'Hagan DT, Van Der Most R, Rappuoli R, Villinger F, Kleanthous H, Rappaport J, Suthar MS, Veesler D, Wang TT, King NP, Pulendran B. Arunachalam PS, et al. Among authors: veesler d. Sci Transl Med. 2022 Aug 17;14(658):eabq4130. doi: 10.1126/scitranslmed.abq4130. Epub 2022 Aug 17. Sci Transl Med. 2022. PMID: 35976993 Free PMC article.
186 results