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Cytochrome P450 and flavin-containing monooxygenase enzymes are responsible for differential oxidation of the anti-thyroid-cancer drug vandetanib by human and rat hepatic microsomal systems.
Indra R, Pompach P, Vavrová K, Jáklová K, Heger Z, Adam V, Eckschlager T, Kopečková K, Arlt VM, Stiborová M. Indra R, et al. Among authors: vavrova k. Environ Toxicol Pharmacol. 2020 Feb;74:103310. doi: 10.1016/j.etap.2019.103310. Epub 2019 Dec 3. Environ Toxicol Pharmacol. 2020. PMID: 31837525
Both Nitro Groups Are Essential for High Antitubercular Activity of 3,5-Dinitrobenzylsulfanyl Tetrazoles and 1,3,4-Oxadiazoles through the Deazaflavin-Dependent Nitroreductase Activation Pathway.
Karabanovich G, Fabiánová V, Vocat A, Dušek J, Valášková L, Stolaříková J, Kitson RRA, Pávek P, Vávrová K, Djaout K, Mikušová K, Baulard AR, Cole ST, Korduláková J, Roh J. Karabanovich G, et al. Among authors: vavrova k. J Med Chem. 2024 Jan 11;67(1):81-109. doi: 10.1021/acs.jmedchem.3c00925. Epub 2023 Dec 29. J Med Chem. 2024. PMID: 38157261 Free PMC article.
Topical Drug Delivery of Concentrated Cabazitaxel in an α-Tocopherol and DMSO Solution.
Sun B, Paraskevopoulos G, Min J, Rossdeutcher R, Ghosh S, Quinn B, Lin MH, Sarkar D, Sukumaran D, Wang Y, Vávrová K, Lovell JF, Zhang Y. Sun B, et al. Among authors: vavrova k. Adv Sci (Weinh). 2023 Oct;10(29):e2302658. doi: 10.1002/advs.202302658. Epub 2023 Aug 9. Adv Sci (Weinh). 2023. PMID: 37555802 Free PMC article.
136 results