Vaughn JP - Search Results

1

The RNA helicase DHX36-G4R1 modulates C9orf72 GGGGCC hexanucleotide repeat-associated translation.

Tseng YJ, Sandwith SN, Green KM, Chambers AE, Krans A, Raimer HM, Sharlow ME, Reisinger MA, Richardson AE, Routh ED, Smaldino MA, Wang YH, Vaughn JP, Todd PK, Smaldino PJ. Tseng YJ, et al. Among authors: vaughn jp. J Biol Chem. 2021 Aug;297(2):100914. doi: 10.1016/j.jbc.2021.100914. Epub 2021 Jun 24. J Biol Chem. 2021. PMID: 34174288 Free PMC article.

2

The DEXH protein product of the DHX36 gene is the major source of tetramolecular quadruplex G4-DNA resolving activity in HeLa cell lysates.

Vaughn JP, Creacy SD, Routh ED, Joyner-Butt C, Jenkins GS, Pauli S, Nagamine Y, Akman SA. Vaughn JP, et al. J Biol Chem. 2005 Nov 18;280(46):38117-20. doi: 10.1074/jbc.C500348200. Epub 2005 Sep 7. J Biol Chem. 2005. PMID: 16150737 Free article.

3

G4 resolvase 1 binds both DNA and RNA tetramolecular quadruplex with high affinity and is the major source of tetramolecular quadruplex G4-DNA and G4-RNA resolving activity in HeLa cell lysates.

Creacy SD, Routh ED, Iwamoto F, Nagamine Y, Akman SA, Vaughn JP. Creacy SD, et al. Among authors: vaughn jp. J Biol Chem. 2008 Dec 12;283(50):34626-34. doi: 10.1074/jbc.M806277200. Epub 2008 Oct 7. J Biol Chem. 2008. PMID: 18842585 Free PMC article.

4

G4 resolvase 1 tightly binds and unwinds unimolecular G4-DNA.

Giri B, Smaldino PJ, Thys RG, Creacy SD, Routh ED, Hantgan RR, Lattmann S, Nagamine Y, Akman SA, Vaughn JP. Giri B, et al. Among authors: vaughn jp. Nucleic Acids Res. 2011 Sep 1;39(16):7161-78. doi: 10.1093/nar/gkr234. Epub 2011 May 17. Nucleic Acids Res. 2011. PMID: 21586581 Free PMC article.

5

Yin Yang 1 contains G-quadruplex structures in its promoter and 5'-UTR and its expression is modulated by G4 resolvase 1.

Huang W, Smaldino PJ, Zhang Q, Miller LD, Cao P, Stadelman K, Wan M, Giri B, Lei M, Nagamine Y, Vaughn JP, Akman SA, Sui G. Huang W, et al. Among authors: vaughn jp. Nucleic Acids Res. 2012 Feb;40(3):1033-49. doi: 10.1093/nar/gkr849. Epub 2011 Oct 12. Nucleic Acids Res. 2012. PMID: 21993297 Free PMC article.

6

Mutational Dissection of Telomeric DNA Binding Requirements of G4 Resolvase 1 Shows that G4-Structure and Certain 3'-Tail Sequences Are Sufficient for Tight and Complete Binding.

Smaldino PJ, Routh ED, Kim JH, Giri B, Creacy SD, Hantgan RR, Akman SA, Vaughn JP. Smaldino PJ, et al. Among authors: vaughn jp. PLoS One. 2015 Jul 14;10(7):e0132668. doi: 10.1371/journal.pone.0132668. eCollection 2015. PLoS One. 2015. PMID: 26172836 Free PMC article.

7

A G-quadruplex DNA-affinity Approach for Purification of Enzymatically Active G4 Resolvase1.

Routh ED, Creacy SD, Beerbower PE, Akman SA, Vaughn JP, Smaldino PJ. Routh ED, et al. Among authors: vaughn jp. J Vis Exp. 2017 Mar 18;(121):55496. doi: 10.3791/55496. J Vis Exp. 2017. PMID: 28362374 Free PMC article.

8

G-Quadruplex Helicase DHX36/G4R1 Engages Nuclear Lamina Proteins in Quiescent Breast Cancer Cells.

Richardson AE, Zentz ZA, Chambers AE, Sandwith SN, Reisinger MA, Saunders DW, Tompkins JD, Riggs AD, Routh ED, Rubenstein EM, Smaldino MA, Vaughn JP, Haney RA, Smaldino PJ. Richardson AE, et al. Among authors: vaughn jp. ACS Omega. 2020 Sep 16;5(38):24916-24926. doi: 10.1021/acsomega.0c03723. eCollection 2020 Sep 29. ACS Omega. 2020. PMID: 33015511 Free PMC article.

9

Differential Gene Expression following DHX36/G4R1 Knockout Is Associated with G-Quadruplex Content and Cancer.

Gumina JM, Richardson AE, Shojiv MH, Chambers AE, Sandwith SN, Reisinger MA, Karns TJ, Osborne TL, Alashi HN, Anderson QT, Sharlow ME, Seiler DC, Rogers EM, Bartosik AR, Smaldino MA, Vaughn JP, Wang YH, Smaldino PJ, Haney RA. Gumina JM, et al. Among authors: vaughn jp. Int J Mol Sci. 2024 Feb 1;25(3):1753. doi: 10.3390/ijms25031753. Int J Mol Sci. 2024. PMID: 38339029 Free PMC article.

10

Amplification of DNA sequences in mammalian cells.

Hamlin JL, Leu TH, Vaughn JP, Ma C, Dijkwel PA. Hamlin JL, et al. Among authors: vaughn jp. Prog Nucleic Acid Res Mol Biol. 1991;41:203-39. doi: 10.1016/s0079-6603(08)60010-0. Prog Nucleic Acid Res Mol Biol. 1991. PMID: 1882075 Review. No abstract available.

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