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113 results

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Page 1
Proximity-Induced Nucleic Acid Degrader (PINAD) Approach to Targeted RNA Degradation Using Small Molecules.
Mikutis S, Rebelo M, Yankova E, Gu M, Tang C, Coelho AR, Yang M, Hazemi ME, Pires de Miranda M, Eleftheriou M, Robertson M, Vassiliou GS, Adams DJ, Simas JP, Corzana F, Schneekloth JS Jr, Tzelepis K, Bernardes GJL. Mikutis S, et al. Among authors: vassiliou gs. ACS Cent Sci. 2023 Apr 26;9(5):892-904. doi: 10.1021/acscentsci.3c00015. eCollection 2023 May 24. ACS Cent Sci. 2023. PMID: 37252343 Free PMC article.
Genotoxic aldehyde stress prematurely ages hematopoietic stem cells in a p53-driven manner.
Wang M, Brandt LTL, Wang X, Russell H, Mitchell E, Kamimae-Lanning AN, Brown JM, Dingler FA, Garaycoechea JI, Isobe T, Kinston SJ, Gu M, Vassiliou GS, Wilson NK, Göttgens B, Patel KJ. Wang M, et al. Among authors: vassiliou gs. Mol Cell. 2023 Jul 20;83(14):2417-2433.e7. doi: 10.1016/j.molcel.2023.05.035. Epub 2023 Jun 21. Mol Cell. 2023. PMID: 37348497 Free PMC article.
Clonal hematopoiesis with DNMT3A and PPM1D mutations impairs regeneration in autologous stem cell transplant recipients.
Stelmach P, Richter S, Sauer S, Fabre MA, Gu M, Rohde C, Janssen M, Liebers N, Proynova R, Weinhold N, Raab MS, Goldschmidt H, Besenbeck B, Pavel P, Laier S, Trumpp A, Dietrich S, Vassiliou GS, Müller-Tidow C. Stelmach P, et al. Among authors: vassiliou gs. Haematologica. 2023 Dec 1;108(12):3308-3320. doi: 10.3324/haematol.2023.282992. Haematologica. 2023. PMID: 37381752 Free PMC article.
Genetic Predisposition to Clonal Hematopoiesis.
Quiros PM, Vassiliou GS. Quiros PM, et al. Among authors: vassiliou gs. Hemasphere. 2023 Aug 17;7(9):e947. doi: 10.1097/HS9.0000000000000947. eCollection 2023 Sep. Hemasphere. 2023. PMID: 37600859 Free PMC article. No abstract available.
Clonal hematopoiesis in people with advanced HIV and associated inflammatory syndromes.
Rocco JM, Zhou Y, Liu NS, Laidlaw E, Galindo F, Anderson MV, Rupert A, Lage SL, Ortega-Villa AM, Yu S, Lisco A, Manion M, Vassiliou GS, Dunbar CE, Sereti I. Rocco JM, et al. Among authors: vassiliou gs. JCI Insight. 2024 Apr 2;9(9):e174783. doi: 10.1172/jci.insight.174783. JCI Insight. 2024. PMID: 38564303 Free article.
SOD1 is a synthetic lethal target in PPM1D-mutant leukemia cells.
Zhang L, Hsu JI, Braekeleer ED, Chen CW, Patel TD, Martell AG, Guzman AG, Wohlan K, Waldvogel SM, Urya H, Tovy A, Callen E, Murdaugh R, Richard R, Jansen S, Vissers L, de Vries BBA, Nussenzweig A, Huang S, Coarfa C, Anastas JN, Takahashi K, Vassiliou G, Goodell MA. Zhang L, et al. bioRxiv [Preprint]. 2024 Jan 17:2023.08.31.555634. doi: 10.1101/2023.08.31.555634. bioRxiv. 2024. PMID: 37693622 Free PMC article. Preprint.
Round Table Discussion on Optimal Clinical Trial Design in Precursor Multiple Myeloma.
Ghobrial IM, Gormley N, Kumar SK, Mateos MV, Bergsagel PL, Chesi M, Dhodapkar MV, Dispenzieri A, Fonseca R, Getz G, Kastritis E, Kristinsson SY, Martinez-Climent JA, Manier S, Marinac CR, Maura F, Morgan GJ, Davies FE, Nadeem O, Nuvolone M, Paiva B, O'Donnell E, Prosper F, Shah UA, Sklavenitis-Pistofidis R, Sperling AS, Vassiliou GS, Munshi NC, Castle PE, Anderson KC, San Miguel JF. Ghobrial IM, et al. Among authors: vassiliou gs. Blood Cancer Discov. 2024 May 1;5(3):146-152. doi: 10.1158/2643-3230.BCD-24-0022. Blood Cancer Discov. 2024. PMID: 38441243
Inherited polygenic effects on common hematological traits influence clonal selection on JAK2V617F and the development of myeloproliferative neoplasms.
Guo J, Walter K, Quiros PM, Gu M, Baxter EJ, Danesh J, Di Angelantonio E, Roberts D, Guglielmelli P, Harrison CN, Godfrey AL, Green AR, Vassiliou GS, Vuckovic D, Nangalia J, Soranzo N. Guo J, et al. Among authors: vassiliou gs. Nat Genet. 2024 Feb;56(2):273-280. doi: 10.1038/s41588-023-01638-x. Epub 2024 Jan 17. Nat Genet. 2024. PMID: 38233595 Free PMC article.
Preleukemic single-cell landscapes reveal mutation-specific mechanisms and gene programs predictive of AML patient outcomes.
Isobe T, Kucinski I, Barile M, Wang X, Hannah R, Bastos HP, Chabra S, Vijayabaskar MS, Sturgess KHM, Williams MJ, Giotopoulos G, Marando L, Li J, Rak J, Gozdecka M, Prins D, Shepherd MS, Watcham S, Green AR, Kent DG, Vassiliou GS, Huntly BJP, Wilson NK, Göttgens B. Isobe T, et al. Among authors: vassiliou gs. Cell Genom. 2023 Oct 27;3(12):100426. doi: 10.1016/j.xgen.2023.100426. eCollection 2023 Dec 13. Cell Genom. 2023. PMID: 38116120 Free PMC article.
113 results