Vasdev N - Search Results

1

Leveraging Open Science Drug Development for PET: Preliminary Neuroimaging of ¹¹C-Labeled ALK2 Inhibitors.

Murrell E, Tong J, Smil D, Kiyota T, Aman AM, Isaac MB, Watson IDG, Vasdev N. Murrell E, et al. Among authors: vasdev n. ACS Med Chem Lett. 2021 Apr 23;12(5):846-850. doi: 10.1021/acsmedchemlett.1c00127. eCollection 2021 May 13. ACS Med Chem Lett. 2021. PMID: 34055235 Free PMC article.

2

Synthesis and ex vivo evaluation of carbon-11 labelled N-(4-methoxybenzyl)-N'-(5-nitro-1,3-thiazol-2-yl)urea ([11C]AR-A014418): a radiolabelled glycogen synthase kinase-3beta specific inhibitor for PET studies.

Vasdev N, Garcia A, Stableford WT, Young AB, Meyer JH, Houle S, Wilson AA. Vasdev N, et al. Bioorg Med Chem Lett. 2005 Dec 1;15(23):5270-3. doi: 10.1016/j.bmcl.2005.08.037. Epub 2005 Oct 3. Bioorg Med Chem Lett. 2005. PMID: 16202587

3

[11C]CURB: Evaluation of a novel radiotracer for imaging fatty acid amide hydrolase by positron emission tomography.

Wilson AA, Garcia A, Parkes J, Houle S, Tong J, Vasdev N. Wilson AA, et al. Among authors: vasdev n. Nucl Med Biol. 2011 Feb;38(2):247-53. doi: 10.1016/j.nucmedbio.2010.08.001. Nucl Med Biol. 2011. PMID: 21315280

4

Radiosynthesis and evaluation of [¹¹C-carbonyl]-labeled carbamates as fatty acid amide hydrolase radiotracers for positron emission tomography.

Wilson AA, Hicks JW, Sadovski O, Parkes J, Tong J, Houle S, Fowler CJ, Vasdev N. Wilson AA, et al. Among authors: vasdev n. J Med Chem. 2013 Jan 10;56(1):201-9. doi: 10.1021/jm301492y. Epub 2012 Dec 19. J Med Chem. 2013. PMID: 23214511 Free PMC article.

5

Synthesis and preclinical evaluation of [11C-carbonyl]PF-04457845 for neuroimaging of fatty acid amide hydrolase.

Hicks JW, Parkes J, Sadovski O, Tong J, Houle S, Vasdev N, Wilson AA. Hicks JW, et al. Among authors: vasdev n. Nucl Med Biol. 2013 Aug;40(6):740-6. doi: 10.1016/j.nucmedbio.2013.04.008. Epub 2013 May 31. Nucl Med Biol. 2013. PMID: 23731552 Free PMC article.

6

Radiosynthesis and ex vivo evaluation of [(11)C-carbonyl]carbamate- and urea-based monoacylglycerol lipase inhibitors.

Hicks JW, Parkes J, Tong J, Houle S, Vasdev N, Wilson AA. Hicks JW, et al. Among authors: vasdev n. Nucl Med Biol. 2014 Sep;41(8):688-94. doi: 10.1016/j.nucmedbio.2014.05.001. Epub 2014 May 10. Nucl Med Biol. 2014. PMID: 24969632 Free PMC article.

7

Classics in Neuroimaging: Development of PET Tracers for Imaging Monoamine Oxidases.

Narayanaswami V, Drake LR, Brooks AF, Meyer JH, Houle S, Kilbourn MR, Scott PJH, Vasdev N. Narayanaswami V, et al. Among authors: vasdev n. ACS Chem Neurosci. 2019 Apr 17;10(4):1867-1871. doi: 10.1021/acschemneuro.9b00081. Epub 2019 Feb 21. ACS Chem Neurosci. 2019. PMID: 30789704 Free PMC article. Review.

8

Synthesis and preclinical evaluation of [¹⁸F]FSL25.1188, a reversible PET radioligand for monoamine oxidase-B.

Dahl K, Bernard-Gauthier V, Nag S, Varnäs K, Narayanaswami V, Mahdi Moein M, Arakawa R, Vasdev N, Halldin C. Dahl K, et al. Among authors: vasdev n. Bioorg Med Chem Lett. 2019 Jul 1;29(13):1624-1627. doi: 10.1016/j.bmcl.2019.04.040. Epub 2019 Apr 27. Bioorg Med Chem Lett. 2019. PMID: 31060887

9

Structural Basis for Achieving GSK-3β Inhibition with High Potency, Selectivity, and Brain Exposure for Positron Emission Tomography Imaging and Drug Discovery.

Bernard-Gauthier V, Mossine AV, Knight A, Patnaik D, Zhao WN, Cheng C, Krishnan HS, Xuan LL, Chindavong PS, Reis SA, Chen JM, Shao X, Stauff J, Arteaga J, Sherman P, Salem N, Bonsall D, Amaral B, Varlow C, Wells L, Martarello L, Patel S, Liang SH, Kurumbail RG, Haggarty SJ, Scott PJH, Vasdev N. Bernard-Gauthier V, et al. Among authors: vasdev n. J Med Chem. 2019 Nov 14;62(21):9600-9617. doi: 10.1021/acs.jmedchem.9b01030. Epub 2019 Oct 21. J Med Chem. 2019. PMID: 31535859 Free PMC article.

10

Revisiting the Radiosynthesis of [¹⁸F]FPEB and Preliminary PET Imaging in a Mouse Model of Alzheimer's Disease.

Varlow C, Murrell E, Holland JP, Kassenbrock A, Shannon W, Liang SH, Vasdev N, Stephenson NA. Varlow C, et al. Among authors: vasdev n. Molecules. 2020 Feb 22;25(4):982. doi: 10.3390/molecules25040982. Molecules. 2020. PMID: 32098347 Free PMC article.

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