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PINK1-Dependent Mitophagy Inhibits Elevated Ubiquitin Phosphorylation Caused by Mitochondrial Damage.
Lambourne OA, Bell S, Wilhelm LP, Yarbrough EB, Holly GG, Russell OM, Alghamdi AM, Fdel AM, Varricchio C, Lane EL, Ganley IG, Jones AT, Goldberg MS, Mehellou Y. Lambourne OA, et al. Among authors: varricchio c. J Med Chem. 2023 Jun 8;66(11):7645-7656. doi: 10.1021/acs.jmedchem.3c00555. Epub 2023 May 29. J Med Chem. 2023. PMID: 37248632 Free PMC article.
Evaluation of the Structure-Activity Relationship of Microtubule-Targeting 1,2,4-Triazolo[1,5-a]pyrimidines Identifies New Candidates for Neurodegenerative Tauopathies.
Oukoloff K, Nzou G, Varricchio C, Lucero B, Alle T, Kovalevich J, Monti L, Cornec AS, Yao Y, James MJ, Trojanowski JQ, Lee VM, Smith AB 3rd, Brancale A, Brunden KR, Ballatore C. Oukoloff K, et al. Among authors: varricchio c. J Med Chem. 2021 Jan 28;64(2):1073-1102. doi: 10.1021/acs.jmedchem.0c01605. Epub 2021 Jan 7. J Med Chem. 2021. PMID: 33411523 Free PMC article.
Microtubule-Stabilizing 1,2,4-Triazolo[1,5-a]pyrimidines as Candidate Therapeutics for Neurodegenerative Disease: Matched Molecular Pair Analyses and Computational Studies Reveal New Structure-Activity Insights.
Alle T, Varricchio C, Yao Y, Lucero B, Nzou G, Demuro S, Muench M, Vuong KD, Oukoloff K, Cornec AS, Francisco KR, Caffrey CR, Lee VM, Smith AB 3rd, Brancale A, Brunden KR, Ballatore C. Alle T, et al. Among authors: varricchio c. J Med Chem. 2023 Jan 12;66(1):435-459. doi: 10.1021/acs.jmedchem.2c01411. Epub 2022 Dec 19. J Med Chem. 2023. PMID: 36534051 Free PMC article.
Structure-Activity Relationship Studies on Novel Antiviral Agents for Norovirus Infections.
Ferla S, Varricchio C, Knight W, Ho PK, Saporito F, Tropea B, Fagan G, Flude BM, Bevilacqua F, Santos-Ferreira N, Van Dycke J, Neyts J, Brancale A, Rocha-Pereira J, Bassetto M. Ferla S, et al. Among authors: varricchio c. Microorganisms. 2021 Aug 24;9(9):1795. doi: 10.3390/microorganisms9091795. Microorganisms. 2021. PMID: 34576691 Free PMC article.
82 results