Varricchio C - Search Results

1

Computational Studies towards the Identification of Novel Rhodopsin-Binding Compounds as Chemical Chaperones for Misfolded Opsins.

Pasqualetto G, Schepelmann M, Varricchio C, Pileggi E, Khogali C, Morgan SR, Boostrom I, Rozanowska M, Brancale A, Ferla S, Bassetto M. Pasqualetto G, et al. Among authors: varricchio c. Molecules. 2020 Oct 23;25(21):4904. doi: 10.3390/molecules25214904. Molecules. 2020. PMID: 33114011 Free PMC article.

2

The ying and yang of idebenone: Not too little, not too much - cell death in NQO1 deficient cells and the mouse retina.

Varricchio C, Beirne K, Heard C, Newland B, Rozanowska M, Brancale A, Votruba M. Varricchio C, et al. Free Radic Biol Med. 2020 May 20;152:551-560. doi: 10.1016/j.freeradbiomed.2019.11.030. Epub 2019 Nov 24. Free Radic Biol Med. 2020. PMID: 31775023

3

In Vitro Topical Delivery of Chlorhexidine to the Cornea: Enhancement Using Drug-Loaded Contact Lenses and β-Cyclodextrin Complexation, and the Importance of Simulating Tear Irrigation.

Hewitt MG, Morrison PWJ, Boostrom HM, Morgan SR, Fallon M, Lewis PN, Whitaker D, Brancale A, Varricchio C, Quantock AJ, Burton MJ, Heard CM. Hewitt MG, et al. Among authors: varricchio c. Mol Pharm. 2020 Apr 6;17(4):1428-1441. doi: 10.1021/acs.molpharmaceut.0c00140. Epub 2020 Mar 20. Mol Pharm. 2020. PMID: 32125863

4

Focal drug administration via heparin-containing cryogel microcarriers reduces cancer growth and metastasis.

Newland B, Varricchio C, Körner Y, Hoppe F, Taplan C, Newland H, Eigel D, Tornillo G, Pette D, Brancale A, Welzel PB, Seib FP, Werner C. Newland B, et al. Among authors: varricchio c. Carbohydr Polym. 2020 Oct 1;245:116504. doi: 10.1016/j.carbpol.2020.116504. Epub 2020 Jun 3. Carbohydr Polym. 2020. PMID: 32718615

5

Discovery of Novel 2-Aniline-1,4-naphthoquinones as Potential New Drug Treatment for Leber's Hereditary Optic Neuropathy (LHON).

Varricchio C, Beirne K, Aeschlimann P, Heard C, Rozanowska M, Votruba M, Brancale A. Varricchio C, et al. J Med Chem. 2020 Nov 25;63(22):13638-13655. doi: 10.1021/acs.jmedchem.0c00942. Epub 2020 Nov 12. J Med Chem. 2020. PMID: 33180495

6

Structure property relationships of N-acylsulfonamides and related bioisosteres.

Francisco KR, Varricchio C, Paniak TJ, Kozlowski MC, Brancale A, Ballatore C. Francisco KR, et al. Among authors: varricchio c. Eur J Med Chem. 2021 Jun 5;218:113399. doi: 10.1016/j.ejmech.2021.113399. Epub 2021 Mar 28. Eur J Med Chem. 2021. PMID: 33823393 Free PMC article.

7

Ligand-based rational design, synthesis and evaluation of novel potential chemical chaperones for opsin.

Pasqualetto G, Pileggi E, Schepelmann M, Varricchio C, Rozanowska M, Brancale A, Bassetto M. Pasqualetto G, et al. Among authors: varricchio c. Eur J Med Chem. 2021 Dec 15;226:113841. doi: 10.1016/j.ejmech.2021.113841. Epub 2021 Sep 17. Eur J Med Chem. 2021. PMID: 34555613

8

Structure-Activity Relationship Studies on Novel Antiviral Agents for Norovirus Infections.

Ferla S, Varricchio C, Knight W, Ho PK, Saporito F, Tropea B, Fagan G, Flude BM, Bevilacqua F, Santos-Ferreira N, Van Dycke J, Neyts J, Brancale A, Rocha-Pereira J, Bassetto M. Ferla S, et al. Among authors: varricchio c. Microorganisms. 2021 Aug 24;9(9):1795. doi: 10.3390/microorganisms9091795. Microorganisms. 2021. PMID: 34576691 Free PMC article.

9

Corrigendum to "structure property relationships of N-Acylsulfonamides and related bioisosteres" European journal of medicinal chemistry, 218 (2021), 113399.

Francisco KR, Varricchio C, Paniak TJ, Kozlowski MC, Brancale A, Ballatore C. Francisco KR, et al. Among authors: varricchio c. Eur J Med Chem. 2021 Dec 15;226:113894. doi: 10.1016/j.ejmech.2021.113894. Epub 2021 Oct 19. Eur J Med Chem. 2021. PMID: 34678530 No abstract available.

10

Identification of SARS-CoV-2 inhibitors targeting Mpro and PLpro using in-cell-protease assay.

Narayanan A, Narwal M, Majowicz SA, Varricchio C, Toner SA, Ballatore C, Brancale A, Murakami KS, Jose J. Narayanan A, et al. Among authors: varricchio c. Commun Biol. 2022 Feb 25;5(1):169. doi: 10.1038/s42003-022-03090-9. Commun Biol. 2022. PMID: 35217718 Free PMC article.

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