Varley PG - Search Results

1

Harnessing secretory pathway differences between HEK293 and CHO to rescue production of difficult to express proteins.

Malm M, Kuo CC, Barzadd MM, Mebrahtu A, Wistbacka N, Razavi R, Volk AL, Lundqvist M, Kotol D, Tegel H, Hober S, Edfors F, Gräslund T, Chotteau V, Field R, Varley PG, Roth RG, Lewis NE, Hatton D, Rockberg J. Malm M, et al. Among authors: varley pg. Metab Eng. 2022 Jul;72:171-187. doi: 10.1016/j.ymben.2022.03.009. Epub 2022 Mar 14. Metab Eng. 2022. PMID: 35301123 Free PMC article.

2

Small-scale bioreactor supports high density HEK293 cell perfusion culture for the production of recombinant Erythropoietin.

Schwarz H, Zhang Y, Zhan C, Malm M, Field R, Turner R, Sellick C, Varley P, Rockberg J, Chotteau V. Schwarz H, et al. J Biotechnol. 2020 Feb 10;309:44-52. doi: 10.1016/j.jbiotec.2019.12.017. Epub 2019 Dec 28. J Biotechnol. 2020. PMID: 31891733

3

Evolution from adherent to suspension: systems biology of HEK293 cell line development.

Malm M, Saghaleyni R, Lundqvist M, Giudici M, Chotteau V, Field R, Varley PG, Hatton D, Grassi L, Svensson T, Nielsen J, Rockberg J. Malm M, et al. Among authors: varley pg. Sci Rep. 2020 Nov 4;10(1):18996. doi: 10.1038/s41598-020-76137-8. Sci Rep. 2020. PMID: 33149219 Free PMC article.

4

Low Shear Stress Increases Recombinant Protein Production and High Shear Stress Increases Apoptosis in Human Cells.

Zhan C, Bidkhori G, Schwarz H, Malm M, Mebrahtu A, Field R, Sellick C, Hatton D, Varley P, Mardinoglu A, Rockberg J, Chotteau V. Zhan C, et al. iScience. 2020 Oct 7;23(11):101653. doi: 10.1016/j.isci.2020.101653. eCollection 2020 Nov 20. iScience. 2020. PMID: 33145483 Free PMC article.

5

Author Correction: Evolution from adherent to suspension: systems biology of HEK293 cell line development.

Malm M, Saghaleyni R, Lundqvist M, Giudici M, Chotteau V, Field R, Varley PG, Hatton D, Grassi L, Svensson T, Nielsen J, Rockberg J. Malm M, et al. Among authors: varley pg. Sci Rep. 2021 Mar 2;11(1):5407. doi: 10.1038/s41598-021-85105-9. Sci Rep. 2021. PMID: 33654173 Free PMC article. No abstract available.

6

Screening for glycosylation changes on recombinant human IgG using lectin methods.

Fotinopoulou A, Meyers T, Varley P, Turner G. Fotinopoulou A, et al. Biotechnol Appl Biochem. 2003 Feb;37(Pt 1):1-7. doi: 10.1042/ba20020023. Biotechnol Appl Biochem. 2003. PMID: 12578544

7

Selective cleavage of human IgG by the matrix metalloproteinases, matrilysin and stromelysin.

Gearing AJ, Thorpe SJ, Miller K, Mangan M, Varley PG, Dudgeon T, Ward G, Turner C, Thorpe R. Gearing AJ, et al. Among authors: varley pg. Immunol Lett. 2002 Apr 1;81(1):41-8. doi: 10.1016/s0165-2478(01)00333-9. Immunol Lett. 2002. PMID: 11841844

8

Novel use of accelerator mass spectrometry for the quantification of low levels of systemic therapeutic recombinant protein.

Lappin G, Garner RC, Meyers T, Powell J, Varley P. Lappin G, et al. J Pharm Biomed Anal. 2006 Jun 16;41(4):1299-302. doi: 10.1016/j.jpba.2006.02.019. Epub 2006 Mar 22. J Pharm Biomed Anal. 2006. PMID: 16554138

9

Identification of amino acid residues critical for aggregation of human CC chemokines macrophage inflammatory protein (MIP)-1alpha, MIP-1beta, and RANTES. Characterization of active disaggregated chemokine variants.

Czaplewski LG, McKeating J, Craven CJ, Higgins LD, Appay V, Brown A, Dudgeon T, Howard LA, Meyers T, Owen J, Palan SR, Tan P, Wilson G, Woods NR, Heyworth CM, Lord BI, Brotherton D, Christison R, Craig S, Cribbes S, Edwards RM, Evans SJ, Gilbert R, Morgan P, Randle E, Schofield N, Varley PG, Fisher J, Waltho JP, Hunter MG. Czaplewski LG, et al. Among authors: varley pg. J Biol Chem. 1999 Jun 4;274(23):16077-84. doi: 10.1074/jbc.274.23.16077. J Biol Chem. 1999. PMID: 10347159 Free article.

10

Chemical modification of a variant of human MIP-1alpha; implications for dimer structure.

Ashfield JT, Meyers T, Lowne D, Varley PG, Arnold JR, Tan P, Yang JC, Czaplewski LG, Dudgeon T, Fisher J. Ashfield JT, et al. Among authors: varley pg. Protein Sci. 2000 Oct;9(10):2047-53. doi: 10.1110/ps.9.10.2047. Protein Sci. 2000. PMID: 11106181 Free PMC article.

Save citations to file

Email citations

Send citations to clipboard

Add to Collections

Add to My Bibliography

Create a file for external citation management software

Your saved search

Your RSS Feed

My NCBI Filters

Text availability

Article attribute

Article type

Publication date

22 results

Search Page