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The ellagic acid derivative 4,4'-di-O-methylellagic acid efficiently inhibits colon cancer cell growth through a mechanism involving WNT16.
Ramírez de Molina A, Vargas T, Molina S, Sánchez J, Martínez-Romero J, González-Vallinas M, Martín-Hernández R, Sánchez-Martínez R, Gómez de Cedrón M, Dávalos A, Calani L, Del Rio D, González-Sarrías A, Espín JC, Tomás-Barberán FA, Reglero G. Ramírez de Molina A, et al. Among authors: vargas t. J Pharmacol Exp Ther. 2015 May;353(2):433-44. doi: 10.1124/jpet.114.221796. Epub 2015 Mar 10. J Pharmacol Exp Ther. 2015. PMID: 25758919
Novel Polyphenols That Inhibit Colon Cancer Cell Growth Affecting Cancer Cell Metabolism.
Gómez de Cedrón M, Vargas T, Madrona A, Jiménez A, Pérez-Pérez MJ, Quintela JC, Reglero G, San-Félix A, Ramírez de Molina A. Gómez de Cedrón M, et al. Among authors: vargas t. J Pharmacol Exp Ther. 2018 Aug;366(2):377-389. doi: 10.1124/jpet.118.248278. Epub 2018 Jun 5. J Pharmacol Exp Ther. 2018. PMID: 29871992
A link between lipid metabolism and epithelial-mesenchymal transition provides a target for colon cancer therapy.
Sánchez-Martínez R, Cruz-Gil S, Gómez de Cedrón M, Álvarez-Fernández M, Vargas T, Molina S, García B, Herranz J, Moreno-Rubio J, Reglero G, Pérez-Moreno M, Feliu J, Malumbres M, Ramírez de Molina A. Sánchez-Martínez R, et al. Among authors: vargas t. Oncotarget. 2015 Nov 17;6(36):38719-36. doi: 10.18632/oncotarget.5340. Oncotarget. 2015. PMID: 26451612 Free PMC article.
173 results