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Discriminating physiological from non-physiological interfaces in structures of protein complexes: A community-wide study.
Schweke H, Xu Q, Tauriello G, Pantolini L, Schwede T, Cazals F, Lhéritier A, Fernandez-Recio J, Rodríguez-Lumbreras LA, Schueler-Furman O, Varga JK, Jiménez-García B, Réau MF, Bonvin AMJJ, Savojardo C, Martelli PL, Casadio R, Tubiana J, Wolfson HJ, Oliva R, Barradas-Bautista D, Ricciardelli T, Cavallo L, Venclovas Č, Olechnovič K, Guerois R, Andreani J, Martin J, Wang X, Terashi G, Sarkar D, Christoffer C, Aderinwale T, Verburgt J, Kihara D, Marchand A, Correia BE, Duan R, Qiu L, Xu X, Zhang S, Zou X, Dey S, Dunbrack RL, Levy ED, Wodak SJ. Schweke H, et al. Among authors: varga jk. Proteomics. 2023 Sep;23(17):e2200323. doi: 10.1002/pmic.202200323. Epub 2023 Jun 27. Proteomics. 2023. PMID: 37365936 Free PMC article.
Who Binds Better? Let Alphafold2 Decide!
Varga JK, Schueler-Furman O. Varga JK, et al. Angew Chem Int Ed Engl. 2023 Jul 10;62(28):e202303526. doi: 10.1002/anie.202303526. Epub 2023 May 15. Angew Chem Int Ed Engl. 2023. PMID: 37114568 Review.
Systematic discovery of protein interaction interfaces using AlphaFold and experimental validation.
Lee CY, Hubrich D, Varga JK, Schäfer C, Welzel M, Schumbera E, Djokic M, Strom JM, Schönfeld J, Geist JL, Polat F, Gibson TJ, Keller Valsecchi CI, Kumar M, Schueler-Furman O, Luck K. Lee CY, et al. Among authors: varga jk. Mol Syst Biol. 2024 Feb;20(2):75-97. doi: 10.1038/s44320-023-00005-6. Epub 2024 Jan 15. Mol Syst Biol. 2024. PMID: 38225382 Free PMC article.
Unbiased phenotype and genotype matching maximizes gene discovery and diagnostic yield.
Rips J, Halstuk O, Fuchs A, Lang Z, Sido T, Gershon-Naamat S, Abu-Libdeh B, Edvardson S, Salah S, Breuer O, Hadhud M, Eden S, Simon I, Slae M, Damseh NS, Abu-Libdeh A, Eskin-Schwartz M, Birk OS, Varga J, Schueler-Furman O, Rosenbluh C, Elpeleg O, Yanovsky-Dagan S, Mor-Shaked H, Harel T. Rips J, et al. Genet Med. 2024 Apr;26(4):101068. doi: 10.1016/j.gim.2024.101068. Epub 2024 Jan 6. Genet Med. 2024. PMID: 38193396
Substrate recognition principles for the PP2A-B55 protein phosphatase.
Kruse T, Garvanska DH, Varga J, Garland W, McEwan B, Hein JB, Weisser MB, Puy IB, Chan CB, Parrila PS, Mendez BL, Arulanandam J, Schueler-Furman O, Jensen TH, Kettenbach A, Nilsson J. Kruse T, et al. bioRxiv [Preprint]. 2024 Feb 13:2024.02.10.579793. doi: 10.1101/2024.02.10.579793. bioRxiv. 2024. PMID: 38370611 Free PMC article. Preprint.
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