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Endotrophin triggers adipose tissue fibrosis and metabolic dysfunction.
Sun K, Park J, Gupta OT, Holland WL, Auerbach P, Zhang N, Goncalves Marangoni R, Nicoloro SM, Czech MP, Varga J, Ploug T, An Z, Scherer PE. Sun K, et al. Among authors: varga j. Nat Commun. 2014 Mar 19;5:3485. doi: 10.1038/ncomms4485. Nat Commun. 2014. PMID: 24647224 Free PMC article.
Tenascin-C drives persistence of organ fibrosis.
Bhattacharyya S, Wang W, Morales-Nebreda L, Feng G, Wu M, Zhou X, Lafyatis R, Lee J, Hinchcliff M, Feghali-Bostwick C, Lakota K, Budinger GR, Raparia K, Tamaki Z, Varga J. Bhattacharyya S, et al. Among authors: varga j. Nat Commun. 2016 Jun 3;7:11703. doi: 10.1038/ncomms11703. Nat Commun. 2016. PMID: 27256716 Free PMC article.
Adiponectin is an endogenous anti-fibrotic mediator and therapeutic target.
Marangoni RG, Masui Y, Fang F, Korman B, Lord G, Lee J, Lakota K, Wei J, Scherer PE, Otvos L, Yamauchi T, Kubota N, Kadowaki T, Asano Y, Sato S, Tourtellotte WG, Varga J. Marangoni RG, et al. Among authors: varga j. Sci Rep. 2017 Jun 30;7(1):4397. doi: 10.1038/s41598-017-04162-1. Sci Rep. 2017. PMID: 28667272 Free PMC article.
Fibroblast A20 governs fibrosis susceptibility and its repression by DREAM promotes fibrosis in multiple organs.
Wang W, Bale S, Wei J, Yalavarthi B, Bhattacharyya D, Yan JJ, Abdala-Valencia H, Xu D, Sun H, Marangoni RG, Herzog E, Berdnikovs S, Miller SD, Sawalha AH, Tsou PS, Awaji K, Yamashita T, Sato S, Asano Y, Tiruppathi C, Yeldandi A, Schock BC, Bhattacharyya S, Varga J. Wang W, et al. Among authors: varga j. Nat Commun. 2022 Oct 26;13(1):6358. doi: 10.1038/s41467-022-33767-y. Nat Commun. 2022. PMID: 36289219 Free PMC article.
1,224 results