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Paired Somatic-Germline Testing of 15 Polyposis and Colorectal Cancer-Predisposing Genes Highlights the Role of APC Mosaicism in de Novo Familial Adenomatous Polyposis.
Rofes P, González S, Navarro M, Moreno-Cabrera JM, Solanes A, Darder E, Carrasco E, Iglesias S, Salinas M, Gómez C, Velasco À, Tuset N, Varela M, Llort G, Ramon Y Cajal T, Grau È, Dueñas N, de la Ossa Merlano N, Matías-Guiu X, Rivera B, Balmaña J, Pineda M, Brunet J, Capellá G, Del Valle J, Lázaro C. Rofes P, et al. Among authors: varela m. J Mol Diagn. 2021 Nov;23(11):1452-1459. doi: 10.1016/j.jmoldx.2021.07.024. Epub 2021 Aug 25. J Mol Diagn. 2021. PMID: 34454113 Free article.
Optimization of RAS/BRAF Mutational Analysis Confirms Improvement in Patient Selection for Clinical Benefit to Anti-EGFR Treatment in Metastatic Colorectal Cancer.
Santos C, Azuara D, Garcia-Carbonero R, Alfonso PG, Carrato A, Elez ME, Gomez A, Losa F, Montagut C, Massuti B, Navarro V, Varela M, Lopez-Doriga A, Moreno V, Valladares M, Manzano JL, Vieitez JM, Aranda E, Sanjuan X, Tabernero J, Capella G, Salazar R. Santos C, et al. Among authors: varela m. Mol Cancer Ther. 2017 Sep;16(9):1999-2007. doi: 10.1158/1535-7163.MCT-17-0153. Epub 2017 Jun 16. Mol Cancer Ther. 2017. PMID: 28626084 Free article.
Clinical performance evaluation of the Idylla™ EGFR Mutation Test on formalin-fixed paraffin-embedded tissue of non-small cell lung cancer.
Delgado-García M, Weynand B, Gómez-Izquierdo L, Hernández MJ, Blanco ÁM, Varela M, Matias-Guiu X, Nadal E, Márquez-Lobo B, Alarcão A, de Álava E, Biscuola M. Delgado-García M, et al. Among authors: varela m. BMC Cancer. 2020 Apr 3;20(1):275. doi: 10.1186/s12885-020-6697-7. BMC Cancer. 2020. PMID: 32245434 Free PMC article.
Validation of Modaplex POLE mutation assay in endometrial carcinoma.
Dorca E, Velasco A, Varela M, Gatius S, Villatoro S, Fullana N, Cuevas D, Vaquero M, Birnbaum A, Neumann K, Matias-Guiu X. Dorca E, et al. Among authors: varela m. Virchows Arch. 2023 Dec;483(6):787-794. doi: 10.1007/s00428-023-03636-0. Epub 2023 Oct 24. Virchows Arch. 2023. PMID: 37874375 Free PMC article.
Molecular profiling and feasibility using a comprehensive hybrid capture panel on a consecutive series of non-small-cell lung cancer patients from a single centre.
Mosteiro M, Azuara D, Villatoro S, Alay A, Gausachs M, Varela M, Baixeras N, Pijuan L, Ajenjo-Bauza M, Lopez-Doriga A, Teulé Á, Solanes A, Palmero R, Brenes J, Jové M, Padrones S, Moreno V, Cordero D, Matías-Guiu X, Lázaro C, Nadal E. Mosteiro M, et al. Among authors: varela m. ESMO Open. 2023 Dec;8(6):102197. doi: 10.1016/j.esmoop.2023.102197. Epub 2023 Dec 8. ESMO Open. 2023. PMID: 38070435 Free PMC article.
Clonal relationship in multisited mucosa-associated lymphoid tissue lymphomas: a single-centre experience.
Condom M, Climent F, Fernández D, Colomer D, Lopez-Guerra M, Varela M, Carro I, Maluquer C, Mercadal S, Oliveira AC, Pané M, Matias-Guiu X, González-Barca E, Sureda A, Domingo-Domenech E. Condom M, et al. Among authors: varela m. Br J Haematol. 2021 Mar;192(6):1020-1025. doi: 10.1111/bjh.16717. Epub 2020 May 23. Br J Haematol. 2021. PMID: 32445250 Free article. Clinical Trial.
Comparison of the Idylla™ MSI assay with the Promega™ MSI Analysis System and immunohistochemistry on formalin-fixed paraffin-embedded tissue of endometrial carcinoma: results from an international, multicenter study.
Gatius S, Velasco A, Varela M, Cuatrecasas M, Jares P, Setaffy L, Bonhomme B, Santon A, Lindemann K, Croce S, Davidson B, Lax S, Palacios J, Matias-Guiu X. Gatius S, et al. Among authors: varela m. Virchows Arch. 2022 May;480(5):1031-1039. doi: 10.1007/s00428-022-03291-x. Epub 2022 Feb 5. Virchows Arch. 2022. PMID: 35124717
Driver mutations in GNAQ and GNA11 genes as potential targets for precision immunotherapy in uveal melanoma patients.
García-Mulero S, Fornelino R, Punta M, Lise S, Varela M, Del Carpio LP, Moreno R, Costa-García M, Rieder D, Trajanoski Z, Gros A, Alemany R, Piulats JM, Sanz-Pamplona R. García-Mulero S, et al. Among authors: varela m. Oncoimmunology. 2023 Oct 24;12(1):2261278. doi: 10.1080/2162402X.2023.2261278. eCollection 2023. Oncoimmunology. 2023. PMID: 38126027 Free PMC article.
833 results