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Image-based and machine learning-guided multiplexed serology test for SARS-CoV-2.
Pietiäinen V, Polso M, Migh E, Guckelsberger C, Harmati M, Diosdi A, Turunen L, Hassinen A, Potdar S, Koponen A, Sebestyen EG, Kovacs F, Kriston A, Hollandi R, Burian K, Terhes G, Visnyovszki A, Fodor E, Lacza Z, Kantele A, Kolehmainen P, Kakkola L, Strandin T, Levanov L, Kallioniemi O, Kemeny L, Julkunen I, Vapalahti O, Buzas K, Paavolainen L, Horvath P, Hepojoki J. Pietiäinen V, et al. Among authors: vapalahti o. Cell Rep Methods. 2023 Aug 22;3(8):100565. doi: 10.1016/j.crmeth.2023.100565. eCollection 2023 Aug 28. Cell Rep Methods. 2023. PMID: 37671026 Free PMC article.
SARS-CoV-2 Infection of Human Neurons Is TMPRSS2 Independent, Requires Endosomal Cell Entry, and Can Be Blocked by Inhibitors of Host Phosphoinositol-5 Kinase.
Kettunen P, Lesnikova A, Räsänen N, Ojha R, Palmunen L, Laakso M, Lehtonen Š, Kuusisto J, Pietiläinen O, Saber SH, Joensuu M, Vapalahti OP, Koistinaho J, Rolova T, Balistreri G. Kettunen P, et al. Among authors: vapalahti op. J Virol. 2023 Apr 27;97(4):e0014423. doi: 10.1128/jvi.00144-23. Epub 2023 Apr 11. J Virol. 2023. PMID: 37039676 Free PMC article.
Human-derived air-liquid interface cultures decipher Alzheimer's disease-SARS-CoV-2 crosstalk in the olfactory mucosa.
Shahbaz MA, Kuivanen S, Lampinen R, Mussalo L, Hron T, Závodná T, Ojha R, Krejčík Z, Saveleva L, Tahir NA, Kalapudas J, Koivisto AM, Penttilä E, Löppönen H, Singh P, Topinka J, Vapalahti O, Chew S, Balistreri G, Kanninen KM. Shahbaz MA, et al. Among authors: vapalahti o. J Neuroinflammation. 2023 Dec 14;20(1):299. doi: 10.1186/s12974-023-02979-4. J Neuroinflammation. 2023. PMID: 38098019 Free PMC article.
Ancestral allele of DNA polymerase gamma modifies antiviral tolerance.
Kang Y, Hepojoki J, Maldonado RS, Mito T, Terzioglu M, Manninen T, Kant R, Singh S, Othman A, Verma R, Uusimaa J, Wartiovaara K, Kareinen L, Zamboni N, Nyman TA, Paetau A, Kipar A, Vapalahti O, Suomalainen A. Kang Y, et al. Among authors: vapalahti o. Nature. 2024 Apr;628(8009):844-853. doi: 10.1038/s41586-024-07260-z. Epub 2024 Apr 3. Nature. 2024. PMID: 38570685 Free PMC article.
Phylogenetic Characterization of Orthohantavirus dobravaense (Dobrava Virus).
Erdin M, Polat C, Smura T, Irmak S, Cetintas O, Cogal M, Colak F, Karatas A, Sozen M, Matur F, Vapalahti O, Sironen T, Oktem IMA. Erdin M, et al. Among authors: vapalahti o. Emerg Infect Dis. 2024 Apr;30(4):779-782. doi: 10.3201/eid3004.230912. Emerg Infect Dis. 2024. PMID: 38526228 Free PMC article.
Double-blinded, randomised, placebo-controlled trial of convalescent plasma for COVID-19: analyses by neutralising antibodies homologous to recipients' variants.
Khawaja T, Kajova M, Levonen I, Pietilä JP, Välimaa H, Paajanen J, Pakkanen SH, Patjas A, Montonen R, Miettinen S, Virtanen J, Smura T, Sironen T, Fagerlund R, Ugurlu H, Iheozor-Ejiofor R, Saksela K, Vahlberg T, Ranki A, Vierikko A, Ihalainen J, Vapalahti O, Kantele A. Khawaja T, et al. Among authors: vapalahti o. Infect Dis (Lond). 2024 Jun;56(6):423-433. doi: 10.1080/23744235.2024.2329957. Epub 2024 Mar 21. Infect Dis (Lond). 2024. PMID: 38513074
The α-dystroglycan N-terminus is a broad-spectrum antiviral agent against SARS-CoV-2 and enveloped viruses.
Bigotti MG, Klein K, Gan ES, Anastasina M, Andersson S, Vapalahti O, Katajisto P, Erdmann M, Davidson AD, Butcher SJ, Collinson I, Ooi EE, Balistreri G, Brancaccio A, Yamauchi Y. Bigotti MG, et al. Among authors: vapalahti o. Antiviral Res. 2024 Apr;224:105837. doi: 10.1016/j.antiviral.2024.105837. Epub 2024 Feb 20. Antiviral Res. 2024. PMID: 38387750 Free article.
438 results