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TIM3+ TRBV11-2 T cells and IFNγ signature in patrolling monocytes and CD16+ NK cells delineate MIS-C.
Hoste L, Roels L, Naesens L, Bosteels V, Vanhee S, Dupont S, Bosteels C, Browaeys R, Vandamme N, Verstaen K, Roels J, Van Damme KFA, Maes B, De Leeuw E, Declercq J, Aegerter H, Seys L, Smole U, De Prijck S, Vanheerswynghels M, Claes K, Debacker V, Van Isterdael G, Backers L, Claes KBM, Bastard P, Jouanguy E, Zhang SY, Mets G, Dehoorne J, Vandekerckhove K, Schelstraete P, Willems J; MIS-C Clinicians; Stordeur P, Janssens S, Beyaert R, Saeys Y, Casanova JL, Lambrecht BN, Haerynck F, Tavernier SJ. Hoste L, et al. J Exp Med. 2022 Feb 7;219(2):e20211381. doi: 10.1084/jem.20211381. Epub 2021 Dec 16. J Exp Med. 2022. PMID: 34914824 Free PMC article.
Integrated gut metabolome and microbiome fingerprinting reveals that dysbiosis precedes allergic inflammation in IgE-mediated pediatric cow's milk allergy.
De Paepe E, Plekhova V, Vangeenderhuysen P, Baeck N, Bullens D, Claeys T, De Graeve M, Kamoen K, Notebaert A, Van de Wiele T, Van Den Broeck W, Vanlede K, Van Winckel M, Vereecke L, Elliott C, Cox E, Vanhaecke L. De Paepe E, et al. Among authors: vanlede k. Allergy. 2024 Apr;79(4):949-963. doi: 10.1111/all.16005. Epub 2024 Jan 9. Allergy. 2024. PMID: 38193259
Blood transcriptomics to facilitate diagnosis and stratification in pediatric rheumatic diseases - a proof of concept study.
Ha MK, Bartholomeus E, Van Os L, Dandelooy J, Leysen J, Aerts O, Siozopoulou V, De Smet E, Gielen J, Guerti K, De Maeseneer M, Herregods N, Lechkar B, Wittoek R, Geens E, Claes L, Zaqout M, Dewals W, Lemay A, Tuerlinckx D, Weynants D, Vanlede K, van Berlaer G, Raes M, Verhelst H, Boiy T, Van Damme P, Jansen AC, Meuwissen M, Sabato V, Van Camp G, Suls A, Werff Ten Bosch JV, Dehoorne J, Joos R, Laukens K, Meysman P, Ogunjimi B. Ha MK, et al. Among authors: vanlede k. Pediatr Rheumatol Online J. 2022 Oct 17;20(1):91. doi: 10.1186/s12969-022-00747-x. Pediatr Rheumatol Online J. 2022. PMID: 36253751 Free PMC article.