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SIK2 inhibition enhances PARP inhibitor activity synergistically in ovarian and triple-negative breast cancers.
Lu Z, Mao W, Yang H, Santiago-O'Farrill JM, Rask PJ, Mondal J, Chen H, Ivan C, Liu X, Liu CG, Xi Y, Masuda K, Carrami EM, Chen M, Tang Y, Pang L, Lakomy DS, Calin GA, Liang H, Ahmed AA, Vankayalapati H, Bast RC Jr. Lu Z, et al. Among authors: vankayalapati h. J Clin Invest. 2022 Jun 1;132(11):e146471. doi: 10.1172/JCI146471. J Clin Invest. 2022. PMID: 35642638 Free PMC article.
A Novel Compound ARN-3236 Inhibits Salt-Inducible Kinase 2 and Sensitizes Ovarian Cancer Cell Lines and Xenografts to Paclitaxel.
Zhou J, Alfraidi A, Zhang S, Santiago-O'Farrill JM, Yerramreddy Reddy VK, Alsaadi A, Ahmed AA, Yang H, Liu J, Mao W, Wang Y, Takemori H, Vankayalapati H, Lu Z, Bast RC Jr. Zhou J, et al. Among authors: vankayalapati h. Clin Cancer Res. 2017 Apr 15;23(8):1945-1954. doi: 10.1158/1078-0432.CCR-16-1562. Epub 2016 Sep 27. Clin Cancer Res. 2017. PMID: 27678456 Free PMC article.
Inhibition of Nek2 by small molecules affects proteasome activity.
Meng L, Carpenter K, Mollard A, Vankayalapati H, Warner SL, Sharma S, Tricot G, Zhan F, Bearss DJ. Meng L, et al. Among authors: vankayalapati h. Biomed Res Int. 2014;2014:273180. doi: 10.1155/2014/273180. Epub 2014 Sep 17. Biomed Res Int. 2014. PMID: 25313354 Free PMC article.
A First-in-Class Inhibitor of ER Coregulator PELP1 Targets ER+ Breast Cancer.
Altwegg KA, Viswanadhapalli S, Mann M, Chakravarty D, Krishnan S, Liu Z, Liu J, Pratap UP, Ebrahimi B, Sanchez JR, Li X, Ma S, Park BH, Santhamma B, Chen Y, Lai Z, Raj GV, Yuan Y, Zhou D, Sareddy GR, Tekmal RR, McHardy S, Huang TH, Rao MK, Vankayalapati H, Vadlamudi RK. Altwegg KA, et al. Among authors: vankayalapati h. Cancer Res. 2022 Oct 17;82(20):3830-3844. doi: 10.1158/0008-5472.CAN-22-0698. Cancer Res. 2022. PMID: 35950923 Free PMC article.
The novel reversible LSD1 inhibitor SP-2577 promotes anti-tumor immunity in SWItch/Sucrose-NonFermentable (SWI/SNF) complex mutated ovarian cancer.
Soldi R, Ghosh Halder T, Weston A, Thode T, Drenner K, Lewis R, Kaadige MR, Srivastava S, Daniel Ampanattu S, Rodriguez Del Villar R, Lang J, Vankayalapati H, Weissman B, Trent JM, Hendricks WPD, Sharma S. Soldi R, et al. Among authors: vankayalapati h. PLoS One. 2020 Jul 10;15(7):e0235705. doi: 10.1371/journal.pone.0235705. eCollection 2020. PLoS One. 2020. PMID: 32649682 Free PMC article.
Innovative therapy for Classic Galactosemia - tale of two HTS.
Tang M, Odejinmi SI, Vankayalapati H, Wierenga KJ, Lai K. Tang M, et al. Among authors: vankayalapati h. Mol Genet Metab. 2012 Jan;105(1):44-55. doi: 10.1016/j.ymgme.2011.09.028. Epub 2011 Oct 1. Mol Genet Metab. 2012. PMID: 22018723 Free PMC article. Review.
Targeting Axl and Mer kinases in cancer.
Verma A, Warner SL, Vankayalapati H, Bearss DJ, Sharma S. Verma A, et al. Among authors: vankayalapati h. Mol Cancer Ther. 2011 Oct;10(10):1763-73. doi: 10.1158/1535-7163.MCT-11-0116. Epub 2011 Sep 20. Mol Cancer Ther. 2011. PMID: 21933973 Review.
43 results