Transformation of renal tubule epithelial cells by simian virus-40 is associated with emergence of Ca(2+)-insensitive K+ channels and altered mitogenic sensitivity to K+ channel blockers.
Teulon J, Ronco PM, Geniteau-Legendre M, Baudouin B, Estrade S, Cassingena R, Vandewalle A.
Teulon J, et al. Among authors: vandewalle a.
J Cell Physiol. 1992 Apr;151(1):113-25. doi: 10.1002/jcp.1041510116.
J Cell Physiol. 1992.
PMID: 1373146
The latter were further characterized by paradoxical effects of Q that induced a marked increase in thymidine incorporation. Q also exerted contrasting effects on channel activity: it inhibited the [K+200 (Ca2+)] when the channel was highly active, with a Ki (0.2 mM …
The latter were further characterized by paradoxical effects of Q that induced a marked increase in thymidine incorporation. Q also e …