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Manipulating mitochondrial electron flow enhances tumor immunogenicity.
Mangalhara KC, Varanasi SK, Johnson MA, Burns MJ, Rojas GR, Esparza Moltó PB, Sainz AG, Tadepalle N, Abbott KL, Mendiratta G, Chen D, Farsakoglu Y, Kunchok T, Hoffmann FA, Parisi B, Rincon M, Vander Heiden MG, Bosenberg M, Hargreaves DC, Kaech SM, Shadel GS. Mangalhara KC, et al. Among authors: vander heiden mg. Science. 2023 Sep 22;381(6664):1316-1323. doi: 10.1126/science.abq1053. Epub 2023 Sep 21. Science. 2023. PMID: 37733872 Free PMC article.
Cancer. Glycosylation to adapt to stress.
Mattaini KR, Vander Heiden MG. Mattaini KR, et al. Among authors: vander heiden mg. Science. 2012 Aug 24;337(6097):925-6. doi: 10.1126/science.1227513. Science. 2012. PMID: 22923571 No abstract available.
Tissue of origin dictates branched-chain amino acid metabolism in mutant Kras-driven cancers.
Mayers JR, Torrence ME, Danai LV, Papagiannakopoulos T, Davidson SM, Bauer MR, Lau AN, Ji BW, Dixit PD, Hosios AM, Muir A, Chin CR, Freinkman E, Jacks T, Wolpin BM, Vitkup D, Vander Heiden MG. Mayers JR, et al. Among authors: vander heiden mg. Science. 2016 Sep 9;353(6304):1161-5. doi: 10.1126/science.aaf5171. Science. 2016. PMID: 27609895 Free PMC article.
The nutrient environment affects therapy.
Muir A, Vander Heiden MG. Muir A, et al. Among authors: vander heiden mg. Science. 2018 Jun 1;360(6392):962-963. doi: 10.1126/science.aar5986. Science. 2018. PMID: 29853672 Free PMC article.
Differential substrate use in EGF- and oncogenic KRAS-stimulated human mammary epithelial cells.
Keibler MA, Dong W, Korthauer KD, Hosios AM, Moon SJ, Sullivan LB, Liu N, Abbott KL, Arevalo OD, Ho K, Lee J, Phanse AS, Kelleher JK, Iliopoulos O, Coloff JL, Vander Heiden MG, Stephanopoulos G. Keibler MA, et al. Among authors: vander heiden mg. FEBS J. 2021 Oct;288(19):5629-5649. doi: 10.1111/febs.15858. Epub 2021 May 13. FEBS J. 2021. PMID: 33811729 Free PMC article.
238 results