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Development of an N-Acyl Amino Acid That Selectively Inhibits the Glycine Transporter 2 To Produce Analgesia in a Rat Model of Chronic Pain.
Mostyn SN, Rawling T, Mohammadi S, Shimmon S, Frangos ZJ, Sarker S, Yousuf A, Vetter I, Ryan RM, Christie MJ, Vandenberg RJ. Mostyn SN, et al. Among authors: vandenberg rj. J Med Chem. 2019 Mar 14;62(5):2466-2484. doi: 10.1021/acs.jmedchem.8b01775. Epub 2019 Feb 20. J Med Chem. 2019. PMID: 30714733 Free PMC article.
Glycine Transporter 2: Mechanism and Allosteric Modulation.
Frangos ZJ, Cantwell Chater RP, Vandenberg RJ. Frangos ZJ, et al. Among authors: vandenberg rj. Front Mol Biosci. 2021 Nov 5;8:734427. doi: 10.3389/fmolb.2021.734427. eCollection 2021. Front Mol Biosci. 2021. PMID: 34805268 Free PMC article. Review.
Peripheral Administration of Selective Glycine Transporter-2 Inhibitor, Oleoyl-D-Lysine, Reverses Chronic Neuropathic Pain but Not Acute or Inflammatory Pain in Male Mice.
Wilson BS, Peiser-Oliver J, Gillis A, Evans S, Alamein C, Mostyn SN, Shimmon S, Rawling T, Christie MJ, Vandenberg RJ, Mohammadi SA. Wilson BS, et al. Among authors: vandenberg rj. J Pharmacol Exp Ther. 2022 Sep;382(3):246-255. doi: 10.1124/jpet.122.001265. Epub 2022 Jul 2. J Pharmacol Exp Ther. 2022. PMID: 35779948
119 results