Vandenberg JI - Search Results

1

High-throughput discovery of trafficking-deficient variants in the cardiac potassium channel K_V11.1.

Kozek KA, Glazer AM, Ng CA, Blackwell D, Egly CL, Vanags LR, Blair M, Mitchell D, Matreyek KA, Fowler DM, Knollmann BC, Vandenberg JI, Roden DM, Kroncke BM. Kozek KA, et al. Among authors: vandenberg ji. Heart Rhythm. 2020 Dec;17(12):2180-2189. doi: 10.1016/j.hrthm.2020.05.041. Epub 2020 Jun 6. Heart Rhythm. 2020. PMID: 32522694 Free PMC article.

2

Human ether-a-go-go related gene (hERG) K+ channels: function and dysfunction.

Perrin MJ, Subbiah RN, Vandenberg JI, Hill AP. Perrin MJ, et al. Among authors: vandenberg ji. Prog Biophys Mol Biol. 2008 Oct-Nov;98(2-3):137-48. doi: 10.1016/j.pbiomolbio.2008.10.006. Epub 2008 Nov 5. Prog Biophys Mol Biol. 2008. PMID: 19027781 Free article. Review.

3

Epistatic effects of potassium channel variation on cardiac repolarization and atrial fibrillation risk.

Mann SA, Otway R, Guo G, Soka M, Karlsdotter L, Trivedi G, Ohanian M, Zodgekar P, Smith RA, Wouters MA, Subbiah R, Walker B, Kuchar D, Sanders P, Griffiths L, Vandenberg JI, Fatkin D. Mann SA, et al. Among authors: vandenberg ji. J Am Coll Cardiol. 2012 Mar 13;59(11):1017-25. doi: 10.1016/j.jacc.2011.11.039. J Am Coll Cardiol. 2012. PMID: 22402074 Free article.

4

Pore helices play a dynamic role as integrators of domain motion during Kv11.1 channel inactivation gating.

Perry MD, Ng CA, Vandenberg JI. Perry MD, et al. Among authors: vandenberg ji. J Biol Chem. 2013 Apr 19;288(16):11482-91. doi: 10.1074/jbc.M113.461442. Epub 2013 Mar 7. J Biol Chem. 2013. PMID: 23471968 Free PMC article.

5

Trafficking defects in PAS domain mutant Kv11.1 channels: roles of reduced domain stability and altered domain-domain interactions.

Ke Y, Ng CA, Hunter MJ, Mann SA, Heide J, Hill AP, Vandenberg JI. Ke Y, et al. Among authors: vandenberg ji. Biochem J. 2013 Aug 15;454(1):69-77. doi: 10.1042/BJ20130328. Biochem J. 2013. PMID: 23721480

6

Hydrophobic interactions between the voltage sensor and pore mediate inactivation in Kv11.1 channels.

Perry MD, Wong S, Ng CA, Vandenberg JI. Perry MD, et al. Among authors: vandenberg ji. J Gen Physiol. 2013 Sep;142(3):275-88. doi: 10.1085/jgp.201310975. J Gen Physiol. 2013. PMID: 23980196 Free PMC article.

7

C-terminal β9-strand of the cyclic nucleotide-binding homology domain stabilizes activated states of Kv11.1 channels.

Ng CA, Ke Y, Perry MD, Tan PS, Hill AP, Vandenberg JI. Ng CA, et al. Among authors: vandenberg ji. PLoS One. 2013 Oct 25;8(10):e77032. doi: 10.1371/journal.pone.0077032. eCollection 2013. PLoS One. 2013. PMID: 24204727 Free PMC article.

8

Kinetics of drug interaction with the Kv11.1 potassium channel.

Hill AP, Perrin MJ, Heide J, Campbell TJ, Mann SA, Vandenberg JI. Hill AP, et al. Among authors: vandenberg ji. Mol Pharmacol. 2014 May;85(5):769-76. doi: 10.1124/mol.114.091835. Epub 2014 Feb 28. Mol Pharmacol. 2014. PMID: 24586056

9

Multiple interactions between cytoplasmic domains regulate slow deactivation of Kv11.1 channels.

Ng CA, Phan K, Hill AP, Vandenberg JI, Perry MD. Ng CA, et al. Among authors: vandenberg ji. J Biol Chem. 2014 Sep 12;289(37):25822-32. doi: 10.1074/jbc.M114.558379. Epub 2014 Jul 29. J Biol Chem. 2014. PMID: 25074935 Free PMC article.

10

Multiscale cardiac modelling reveals the origins of notched T waves in long QT syndrome type 2.

Sadrieh A, Domanski L, Pitt-Francis J, Mann SA, Hodkinson EC, Ng CA, Perry MD, Taylor JA, Gavaghan D, Subbiah RN, Vandenberg JI, Hill AP. Sadrieh A, et al. Among authors: vandenberg ji. Nat Commun. 2014 Sep 25;5:5069. doi: 10.1038/ncomms6069. Nat Commun. 2014. PMID: 25254353 Free article.

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