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Fungal gasdermin-like proteins are controlled by proteolytic cleavage.
Clavé C, Dyrka W, Turcotte EA, Granger-Farbos A, Ibarlosa L, Pinson B, Vance RE, Saupe SJ, Daskalov A. Clavé C, et al. Among authors: vance re. Proc Natl Acad Sci U S A. 2022 Feb 15;119(7):e2109418119. doi: 10.1073/pnas.2109418119. Proc Natl Acad Sci U S A. 2022. PMID: 35135876 Free PMC article.
Molecular characterization of a fungal gasdermin-like protein.
Daskalov A, Mitchell PS, Sandstrom A, Vance RE, Glass NL. Daskalov A, et al. Among authors: vance re. Proc Natl Acad Sci U S A. 2020 Aug 4;117(31):18600-18607. doi: 10.1073/pnas.2004876117. Epub 2020 Jul 23. Proc Natl Acad Sci U S A. 2020. PMID: 32703806 Free PMC article.
NAIP-NLRC4-deficient mice are susceptible to shigellosis.
Mitchell PS, Roncaioli JL, Turcotte EA, Goers L, Chavez RA, Lee AY, Lesser CF, Rauch I, Vance RE. Mitchell PS, et al. Among authors: vance re. Elife. 2020 Oct 19;9:e59022. doi: 10.7554/eLife.59022. Elife. 2020. PMID: 33074100 Free PMC article.
Gasdermin-D and Caspase-7 are the key Caspase-1/8 substrates downstream of the NAIP5/NLRC4 inflammasome required for restriction of Legionella pneumophila.
Gonçalves AV, Margolis SR, Quirino GFS, Mascarenhas DPA, Rauch I, Nichols RD, Ansaldo E, Fontana MF, Vance RE, Zamboni DS. Gonçalves AV, et al. Among authors: vance re. PLoS Pathog. 2019 Jun 28;15(6):e1007886. doi: 10.1371/journal.ppat.1007886. eCollection 2019 Jun. PLoS Pathog. 2019. PMID: 31251782 Free PMC article.
124 results