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Bi-allelic variants in NAE1 cause intellectual disability, ischiopubic hypoplasia, stress-mediated lymphopenia and neurodegeneration.
Muffels IJJ, Schene IF, Rehmann H, Massink MPG, van der Wal MM, Bauder C, Labeur M, Armando NG, Lequin MH, Houben ML, Giltay JC, Haitjema S, Huisman A, Vansenne F, Bluvstein J, Pappas J, Shailee LV, Zarate YA, Mokry M, van Haaften GW, Nieuwenhuis EES, Refojo D, van Wijk F, Fuchs SA, van Hasselt PM. Muffels IJJ, et al. Among authors: van der wal mm. Am J Hum Genet. 2023 Jan 5;110(1):146-160. doi: 10.1016/j.ajhg.2022.12.003. Am J Hum Genet. 2023. PMID: 36608681 Free PMC article.
T cell interaction with activated endothelial cells primes for tissue-residency.
Wienke J, Veldkamp SR, Struijf EM, Yousef Yengej FA, van der Wal MM, van Royen-Kerkhof A, van Wijk F. Wienke J, et al. Among authors: van der wal mm. Front Immunol. 2022 Sep 12;13:827786. doi: 10.3389/fimmu.2022.827786. eCollection 2022. Front Immunol. 2022. PMID: 36172363 Free PMC article.
Siglec-1 expression on monocytes is associated with the interferon signature in juvenile dermatomyositis and can predict treatment response.
Lerkvaleekul B, Veldkamp SR, van der Wal MM, Schatorjé EJH, Kamphuis SSM, van den Berg JM, Hissink Muller PCE, Armbrust W, Vastert SJ, Wienke J, Jansen MHA, van Royen-Kerkhof A, van Wijk F. Lerkvaleekul B, et al. Among authors: van der wal mm. Rheumatology (Oxford). 2022 May 5;61(5):2144-2155. doi: 10.1093/rheumatology/keab601. Rheumatology (Oxford). 2022. PMID: 34387304 Free PMC article.
Early and Long-Term Effects of Dupilumab Treatment on Circulating T-Cell Functions in Patients with Moderate-to-Severe Atopic Dermatitis.
Bakker DS, van der Wal MM, Heeb LEM, Giovannone B, Asamoah M, Delemarre EM, Drylewicz J, Nierkens S, Boyman O, de Bruin-Weller MS, Thijs JL, van Wijk F. Bakker DS, et al. Among authors: van der wal mm. J Invest Dermatol. 2021 Aug;141(8):1943-1953.e13. doi: 10.1016/j.jid.2021.01.022. Epub 2021 Feb 18. J Invest Dermatol. 2021. PMID: 33610558 Free article.
PD-1+CD8+ T cells are clonally expanding effectors in human chronic inflammation.
Petrelli A, Mijnheer G, Hoytema van Konijnenburg DP, van der Wal MM, Giovannone B, Mocholi E, Vazirpanah N, Broen JC, Hijnen D, Oldenburg B, Coffer PJ, Vastert SJ, Prakken BJ, Spierings E, Pandit A, Mokry M, van Wijk F. Petrelli A, et al. Among authors: van der wal mm. J Clin Invest. 2018 Oct 1;128(10):4669-4681. doi: 10.1172/JCI96107. Epub 2018 Aug 2. J Clin Invest. 2018. PMID: 30198907 Free PMC article. Clinical Trial.