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An antibiofilm coating of 5-aryl-2-aminoimidazole covalently attached to a titanium surface.
Peeters E, Hooyberghs G, Robijns S, De Weerdt A, Kucharíková S, Tournu H, Braem A, Čeh K, Majdič G, Španič T, Pogorevc E, Claes B, Dovgan B, Girandon L, Impellizzeri F, Erdtmann M, Krona A, Vleugels J, Fröhlich M, Garcia-Forgas J, De Brucker K, Cammue BPA, Thevissen K, Van Dijck P, Vanderleyden J, Van der Eycken E, Steenackers HP. Peeters E, et al. Among authors: van dijck p, van der eycken e. J Biomed Mater Res B Appl Biomater. 2019 Aug;107(6):1908-1919. doi: 10.1002/jbm.b.34283. Epub 2018 Dec 13. J Biomed Mater Res B Appl Biomater. 2019. PMID: 30549192
Synthesis and fungicidal activity of 3,5-dichloropyrazin-2(1H)-one derivatives.
François IE, Cammue BP, Bresseleers S, Fleuren H, Hoornaert G, Mehta VP, Modha SG, Van der Eycken EV, Thevissen K. François IE, et al. Among authors: van der eycken ev. Bioorg Med Chem Lett. 2009 Aug 1;19(15):4064-6. doi: 10.1016/j.bmcl.2009.06.024. Epub 2009 Jun 13. Bioorg Med Chem Lett. 2009. PMID: 19556127
Structure-activity relationship of 4(5)-aryl-2-amino-1H-imidazoles, N1-substituted 2-aminoimidazoles and imidazo[1,2-a]pyrimidinium salts as inhibitors of biofilm formation by Salmonella typhimurium and Pseudomonas aeruginosa.
Steenackers HP, Ermolat'ev DS, Savaliya B, De Weerdt A, De Coster D, Shah A, Van der Eycken EV, De Vos DE, Vanderleyden J, De Keersmaecker SC. Steenackers HP, et al. Among authors: van der eycken ev. J Med Chem. 2011 Jan 27;54(2):472-84. doi: 10.1021/jm1011148. Epub 2010 Dec 20. J Med Chem. 2011. PMID: 21174477
Structure-activity relationship of 2-hydroxy-2-aryl-2,3-dihydro-imidazo[1,2-a]pyrimidinium salts and 2N-substituted 4(5)-aryl-2-amino-1H-imidazoles as inhibitors of biofilm formation by Salmonella Typhimurium and Pseudomonas aeruginosa.
Steenackers HP, Ermolat'ev DS, Savaliya B, Weerdt AD, Coster DD, Shah A, Van der Eycken EV, De Vos DE, Vanderleyden J, De Keersmaecker SC. Steenackers HP, et al. Among authors: van der eycken ev. Bioorg Med Chem. 2011 Jun 1;19(11):3462-73. doi: 10.1016/j.bmc.2011.04.026. Epub 2011 Apr 19. Bioorg Med Chem. 2011. PMID: 21550812
Evaluation of the toxicity of 5-aryl-2-aminoimidazole-based biofilm inhibitors against eukaryotic cell lines, bone cells and the nematode Caenorhabditis elegans.
Steenackers H, Dubey A, Robijns S, Ermolat'ev D, Delattin N, Dovgan B, Girandon L, Fröhlich M, De Brucker K, Cammue BP, Thevissen K, Balzarini J, Van der Eycken EV, Vanderleyden J. Steenackers H, et al. Molecules. 2014 Oct 16;19(10):16707-23. doi: 10.3390/molecules191016707. Molecules. 2014. PMID: 25325155 Free PMC article.
Modulation of the Substitution Pattern of 5-Aryl-2-Aminoimidazoles Allows Fine-Tuning of Their Antibiofilm Activity Spectrum and Toxicity.
Peeters E, Hooyberghs G, Robijns S, Waldrant K, De Weerdt A, Delattin N, Liebens V, Kucharíková S, Tournu H, Verstraeten N, Dovgan B, Girandon L, Fröhlich M, De Brucker K, Van Dijck P, Michiels J, Cammue BP, Thevissen K, Vanderleyden J, Van der Eycken E, Steenackers HP. Peeters E, et al. Among authors: van dijck p, van der eycken e. Antimicrob Agents Chemother. 2016 Oct 21;60(11):6483-6497. doi: 10.1128/AAC.00035-16. Print 2016 Nov. Antimicrob Agents Chemother. 2016. PMID: 27550355 Free PMC article.
Smart Metal-Organic Framework Coatings: Triggered Antibiofilm Compound Release.
Claes B, Boudewijns T, Muchez L, Hooyberghs G, Van der Eycken EV, Vanderleyden J, Steenackers HP, De Vos DE. Claes B, et al. Among authors: van der eycken ev. ACS Appl Mater Interfaces. 2017 Feb 8;9(5):4440-4449. doi: 10.1021/acsami.6b14152. Epub 2017 Jan 24. ACS Appl Mater Interfaces. 2017. PMID: 28081368
178 results