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Genome-wide association analyses identify 44 risk variants and refine the genetic architecture of major depression.
Wray NR, Ripke S, Mattheisen M, Trzaskowski M, Byrne EM, Abdellaoui A, Adams MJ, Agerbo E, Air TM, Andlauer TMF, Bacanu SA, Bækvad-Hansen M, Beekman AFT, Bigdeli TB, Binder EB, Blackwood DRH, Bryois J, Buttenschøn HN, Bybjerg-Grauholm J, Cai N, Castelao E, Christensen JH, Clarke TK, Coleman JIR, Colodro-Conde L, Couvy-Duchesne B, Craddock N, Crawford GE, Crowley CA, Dashti HS, Davies G, Deary IJ, Degenhardt F, Derks EM, Direk N, Dolan CV, Dunn EC, Eley TC, Eriksson N, Escott-Price V, Kiadeh FHF, Finucane HK, Forstner AJ, Frank J, Gaspar HA, Gill M, Giusti-Rodríguez P, Goes FS, Gordon SD, Grove J, Hall LS, Hannon E, Hansen CS, Hansen TF, Herms S, Hickie IB, Hoffmann P, Homuth G, Horn C, Hottenga JJ, Hougaard DM, Hu M, Hyde CL, Ising M, Jansen R, Jin F, Jorgenson E, Knowles JA, Kohane IS, Kraft J, Kretzschmar WW, Krogh J, Kutalik Z, Lane JM, Li Y, Li Y, Lind PA, Liu X, Lu L, MacIntyre DJ, MacKinnon DF, Maier RM, Maier W, Marchini J, Mbarek H, McGrath P, McGuffin P, Medland SE, Mehta D, Middeldorp CM, Mihailov E, Milaneschi Y, Milani L, Mill J, Mondimore FM, Montgomery GW, Mostafavi S, Mullins N, Nauck M, Ng B, Nivard MG, Nyholt DR, O'Reilly PF, Oskarsson H, Owen MJ, Painter JN, Pede… See abstract for full author list ➔ Wray NR, et al. Among authors: van der auwera s, van hemert am. Nat Genet. 2018 May;50(5):668-681. doi: 10.1038/s41588-018-0090-3. Epub 2018 Apr 26. Nat Genet. 2018. PMID: 29700475 Free PMC article.
Accumulated common variants in the broader fragile X gene family modulate autistic phenotypes.
Stepniak B, Kästner A, Poggi G, Mitjans M, Begemann M, Hartmann A, Van der Auwera S, Sananbenesi F, Krueger-Burg D, Matuszko G, Brosi C, Homuth G, Völzke H, Benseler F, Bagni C, Fischer U, Dityatev A, Grabe HJ, Rujescu D, Fischer A, Ehrenreich H. Stepniak B, et al. Among authors: van der auwera s. EMBO Mol Med. 2015 Dec;7(12):1565-79. doi: 10.15252/emmm.201505696. EMBO Mol Med. 2015. PMID: 26612855 Free PMC article.
Measuring Biological Age via Metabonomics: The Metabolic Age Score.
Hertel J, Friedrich N, Wittfeld K, Pietzner M, Budde K, Van der Auwera S, Lohmann T, Teumer A, Völzke H, Nauck M, Grabe HJ. Hertel J, et al. Among authors: van der auwera s. J Proteome Res. 2016 Feb 5;15(2):400-10. doi: 10.1021/acs.jproteome.5b00561. Epub 2015 Dec 23. J Proteome Res. 2016. PMID: 26652958
Effect of the interaction between childhood abuse and rs1360780 of the FKBP5 gene on gray matter volume in a general population sample.
Grabe HJ, Wittfeld K, Van der Auwera S, Janowitz D, Hegenscheid K, Habes M, Homuth G, Barnow S, John U, Nauck M, Völzke H, Meyer zu Schwabedissen H, Freyberger HJ, Hosten N. Grabe HJ, et al. Among authors: van der auwera s. Hum Brain Mapp. 2016 Apr;37(4):1602-13. doi: 10.1002/hbm.23123. Epub 2016 Jan 27. Hum Brain Mapp. 2016. PMID: 26813705 Free PMC article.
White matter hyperintensities and imaging patterns of brain ageing in the general population.
Habes M, Erus G, Toledo JB, Zhang T, Bryan N, Launer LJ, Rosseel Y, Janowitz D, Doshi J, Van der Auwera S, von Sarnowski B, Hegenscheid K, Hosten N, Homuth G, Völzke H, Schminke U, Hoffmann W, Grabe HJ, Davatzikos C. Habes M, et al. Among authors: van der auwera s. Brain. 2016 Apr;139(Pt 4):1164-79. doi: 10.1093/brain/aww008. Epub 2016 Feb 24. Brain. 2016. PMID: 26912649 Free PMC article.
Sex- and age-specific associations between major depressive disorder and metabolic syndrome in two general population samples in Germany.
Block A, Schipf S, Van der Auwera S, Hannemann A, Nauck M, John U, Völzke H, Freyberger HJ, Dörr M, Felix S, Zygmunt M, Wallaschofski H, Grabe HJ. Block A, et al. Among authors: van der auwera s. Nord J Psychiatry. 2016 Nov;70(8):611-20. doi: 10.1080/08039488.2016.1191535. Epub 2016 Jun 14. Nord J Psychiatry. 2016. PMID: 27299922
The inverse link between genetic risk for schizophrenia and migraine through NMDA (N-methyl-D-aspartate) receptor activation via D-serine.
Van der Auwera S, Teumer A, Hertel J, Homuth G, Völker U, Lucht MJ, Degenhardt F, Schulze T, Rietschel M, Nöthen MM, John U, Nauck M, Grabe HJ. Van der Auwera S, et al. Eur Neuropsychopharmacol. 2016 Sep;26(9):1507-1515. doi: 10.1016/j.euroneuro.2016.03.019. Epub 2016 Jul 6. Eur Neuropsychopharmacol. 2016. PMID: 27394076
115 results