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STING orchestrates the crosstalk between polyunsaturated fatty acid metabolism and inflammatory responses.
Vila IK, Chamma H, Steer A, Saccas M, Taffoni C, Turtoi E, Reinert LS, Hussain S, Marines J, Jin L, Bonnefont X, Hubert M, Schwartz O, Paludan SR, Van Simaeys G, Doumont G, Sobhian B, Vlachakis D, Turtoi A, Laguette N. Vila IK, et al. Among authors: van simaeys g. Cell Metab. 2022 Jan 4;34(1):125-139.e8. doi: 10.1016/j.cmet.2021.12.007. Cell Metab. 2022. PMID: 34986331 Free PMC article.
Myoferlin regulates cellular lipid metabolism and promotes metastases in triple-negative breast cancer.
Blomme A, Costanza B, de Tullio P, Thiry M, Van Simaeys G, Boutry S, Doumont G, Di Valentin E, Hirano T, Yokobori T, Gofflot S, Peulen O, Bellahcène A, Sherer F, Le Goff C, Cavalier E, Mouithys-Mickalad A, Jouret F, Cusumano PG, Lifrange E, Muller RN, Goldman S, Delvenne P, De Pauw E, Nishiyama M, Castronovo V, Turtoi A. Blomme A, et al. Among authors: van simaeys g. Oncogene. 2017 Apr;36(15):2116-2130. doi: 10.1038/onc.2016.369. Epub 2016 Oct 24. Oncogene. 2017. PMID: 27775075
Tristetraprolin expression by keratinocytes controls local and systemic inflammation.
Andrianne M, Assabban A, La C, Mogilenko D, Salle DS, Fleury S, Doumont G, Van Simaeys G, Nedospasov SA, Blackshear PJ, Dombrowicz D, Goriely S, Van Maele L. Andrianne M, et al. Among authors: van maele l, van simaeys g. JCI Insight. 2017 Jun 2;2(11):e92979. doi: 10.1172/jci.insight.92979. eCollection 2017 Jun 2. JCI Insight. 2017. PMID: 28570274 Free PMC article.
N-Acetylcysteine breaks resistance to trastuzumab caused by MUC4 overexpression in human HER2 positive BC-bearing nude mice monitored by 89Zr-Trastuzumab and 18F-FDG PET imaging.
Wimana Z, Gebhart G, Guiot T, Vanderlinden B, Larsimont D, Doumont G, Van Simaeys G, Goldman S, Flamen P, Ghanem G. Wimana Z, et al. Among authors: van simaeys g. Oncotarget. 2017 Apr 10;8(34):56185-56198. doi: 10.18632/oncotarget.17015. eCollection 2017 Aug 22. Oncotarget. 2017. PMID: 28915583 Free PMC article.
Murine stroma adopts a human-like metabolic phenotype in the PDX model of colorectal cancer and liver metastases.
Blomme A, Van Simaeys G, Doumont G, Costanza B, Bellier J, Otaka Y, Sherer F, Lovinfosse P, Boutry S, Palacios AP, De Pauw E, Hirano T, Yokobori T, Hustinx R, Bellahcène A, Delvenne P, Detry O, Goldman S, Nishiyama M, Castronovo V, Turtoi A. Blomme A, et al. Among authors: van simaeys g. Oncogene. 2018 Mar;37(9):1237-1250. doi: 10.1038/s41388-017-0018-x. Epub 2017 Dec 15. Oncogene. 2018. PMID: 29242606
Metastatic colorectal cancer cells maintain the TGFβ program and use TGFBI to fuel angiogenesis.
Chiavarina B, Costanza B, Ronca R, Blomme A, Rezzola S, Chiodelli P, Giguelay A, Belthier G, Doumont G, Van Simaeys G, Lacroix S, Yokobori T, Erkhem-Ochir B, Balaguer P, Cavailles V, Fabbrizio E, Di Valentin E, Gofflot S, Detry O, Jerusalem G, Goldman S, Delvenne P, Bellahcène A, Pannequin J, Castronovo V, Turtoi A. Chiavarina B, et al. Among authors: van simaeys g. Theranostics. 2021 Jan 1;11(4):1626-1640. doi: 10.7150/thno.51507. eCollection 2021. Theranostics. 2021. PMID: 33408771 Free PMC article.
34 results