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A spatial human thymus cell atlas mapped to a continuous tissue axis.
Yayon N, Kedlian VR, Boehme L, Suo C, Wachter B, Beuschel RT, Amsalem O, Polanski K, Koplev S, Tuck E, Dann E, Van Hulle J, Perera S, Putteman T, Predeus AV, Dabrowska M, Richardson L, Tudor C, Kreins AY, Engelbert J, Stephenson E, Kleshchevnikov V, De Rita F, Crossland D, Bosticardo M, Pala F, Prigmore E, Chipampe NJ, Prete M, Fei L, To K, Barker RA, He X, Van Nieuwerburgh F, Bayraktar O, Patel M, Davies GE, Haniffa MA, Uhlmann V, Notarangelo LD, Germain RN, Radtke AJ, Marioni JC, Taghon T, Teichmann SA. Yayon N, et al. Among authors: van hulle j, van nieuwerburgh f. bioRxiv [Preprint]. 2023 Oct 27:2023.10.25.562925. doi: 10.1101/2023.10.25.562925. bioRxiv. 2023. PMID: 37986877 Free PMC article. Preprint.
Human Thymic CD10+ PD-1+ Intraepithelial Lymphocyte Precursors Acquire Interleukin-15 Responsiveness at the CD1a- CD95+ CD28- CCR7- Developmental Stage.
Billiet L, Goetgeluk G, Bonte S, De Munter S, De Cock L, Pille M, Ingels J, Jansen H, Weening K, Van Nieuwerburgh F, Kerre T, Taghon T, Leclercq G, Vandekerckhove B. Billiet L, et al. Among authors: van nieuwerburgh f. Int J Mol Sci. 2020 Nov 20;21(22):8785. doi: 10.3390/ijms21228785. Int J Mol Sci. 2020. PMID: 33233766 Free PMC article.
The transcription factor RUNX2 drives the generation of human NK cells and promotes tissue residency.
Wahlen S, Matthijssens F, Van Loocke W, Taveirne S, Kiekens L, Persyn E, Van Ammel E, De Vos Z, De Munter S, Matthys P, Van Nieuwerburgh F, Taghon T, Vandekerckhove B, Van Vlierberghe P, Leclercq G. Wahlen S, et al. Among authors: van ammel e, van nieuwerburgh f, van loocke w, van vlierberghe p. Elife. 2022 Jul 6;11:e80320. doi: 10.7554/eLife.80320. Elife. 2022. PMID: 35793229 Free PMC article.
Transcriptional dynamics and epigenetic regulation of E and ID protein encoding genes during human T cell development.
Roels J, Van Hulle J, Lavaert M, Kuchmiy A, Strubbe S, Putteman T, Vandekerckhove B, Leclercq G, Van Nieuwerburgh F, Boehme L, Taghon T. Roels J, et al. Among authors: van hulle j, van nieuwerburgh f. Front Immunol. 2022 Jul 28;13:960918. doi: 10.3389/fimmu.2022.960918. eCollection 2022. Front Immunol. 2022. PMID: 35967340 Free PMC article.
TXNIP Promotes Human NK Cell Development but Is Dispensable for NK Cell Functionality.
Persyn E, Wahlen S, Kiekens L, Taveirne S, Van Loocke W, Van Ammel E, Van Nieuwerburgh F, Taghon T, Vandekerckhove B, Van Vlierberghe P, Leclercq G. Persyn E, et al. Among authors: van ammel e, van nieuwerburgh f, van loocke w, van vlierberghe p. Int J Mol Sci. 2022 Sep 26;23(19):11345. doi: 10.3390/ijms231911345. Int J Mol Sci. 2022. PMID: 36232644 Free PMC article.
Intrathymic dendritic cell-biased precursors promote human T cell lineage specification through IRF8-driven transmembrane TNF.
Liang KL, Roels J, Lavaert M, Putteman T, Boehme L, Tilleman L, Velghe I, Pegoretti V, Van de Walle I, Sontag S, Vandewalle J, Vandekerckhove B, Leclercq G, Van Vlierberghe P, Libert C, Van Nieuwerburgh F, Fischer R, Kontermann RE, Pfizenmaier K, Doody G, Zenke M, Taghon T. Liang KL, et al. Among authors: van de walle i, van nieuwerburgh f, van vlierberghe p. Nat Immunol. 2023 Mar;24(3):474-486. doi: 10.1038/s41590-022-01417-6. Epub 2023 Jan 26. Nat Immunol. 2023. PMID: 36703005 Free article.
HES6 knockdown in human hematopoietic precursor cells reduces their in vivo engraftment potential and their capacity to differentiate into erythroid cells, B cells, T cells and plasmacytoid dendritic cells.
De Vos T, Oatman N, Boehme L, Putteman T, Velghe I, Van Droogenbroeck Y, De Munter S, Cesnekova M, Van Nieuwerburgh F, Vandekerckhove B, Philippe J, Taghon T. De Vos T, et al. Among authors: van nieuwerburgh f. Haematologica. 2024 Apr 4. doi: 10.3324/haematol.2023.283432. Online ahead of print. Haematologica. 2024. PMID: 38572564 Free article.
T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells.
Kiekens L, Van Loocke W, Taveirne S, Wahlen S, Persyn E, Van Ammel E, De Vos Z, Matthys P, Van Nieuwerburgh F, Taghon T, Van Vlierberghe P, Vandekerckhove B, Leclercq G. Kiekens L, et al. Among authors: van ammel e, van nieuwerburgh f, van loocke w, van vlierberghe p. Front Immunol. 2021 Sep 24;12:732511. doi: 10.3389/fimmu.2021.732511. eCollection 2021. Front Immunol. 2021. PMID: 34630413 Free PMC article.
253 results