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Targeted degradation of BRD9 reverses oncogenic gene expression in synovial sarcoma.
Brien GL, Remillard D, Shi J, Hemming ML, Chabon J, Wynne K, Dillon ET, Cagney G, Van Mierlo G, Baltissen MP, Vermeulen M, Qi J, Fröhling S, Gray NS, Bradner JE, Vakoc CR, Armstrong SA. Brien GL, et al. Among authors: van mierlo g. Elife. 2018 Nov 15;7:e41305. doi: 10.7554/eLife.41305. Elife. 2018. PMID: 30431433 Free PMC article.
MTF2 recruits Polycomb Repressive Complex 2 by helical-shape-selective DNA binding.
Perino M, van Mierlo G, Karemaker ID, van Genesen S, Vermeulen M, Marks H, van Heeringen SJ, Veenstra GJC. Perino M, et al. Among authors: van heeringen sj, van mierlo g, van genesen s. Nat Genet. 2018 Jul;50(7):1002-1010. doi: 10.1038/s41588-018-0134-8. Epub 2018 May 28. Nat Genet. 2018. PMID: 29808031
The Complexity of PRC2 Subcomplexes.
van Mierlo G, Veenstra GJC, Vermeulen M, Marks H. van Mierlo G, et al. Trends Cell Biol. 2019 Aug;29(8):660-671. doi: 10.1016/j.tcb.2019.05.004. Epub 2019 Jun 6. Trends Cell Biol. 2019. PMID: 31178244 Free article. Review.
PRC2.1 and PRC2.2 Synergize to Coordinate H3K27 Trimethylation.
Healy E, Mucha M, Glancy E, Fitzpatrick DJ, Conway E, Neikes HK, Monger C, Van Mierlo G, Baltissen MP, Koseki Y, Vermeulen M, Koseki H, Bracken AP. Healy E, et al. Among authors: van mierlo g. Mol Cell. 2019 Nov 7;76(3):437-452.e6. doi: 10.1016/j.molcel.2019.08.012. Epub 2019 Sep 11. Mol Cell. 2019. PMID: 31521505 Free article.
Purification and enrichment of specific chromatin loci.
Gauchier M, van Mierlo G, Vermeulen M, Déjardin J. Gauchier M, et al. Among authors: van mierlo g. Nat Methods. 2020 Apr;17(4):380-389. doi: 10.1038/s41592-020-0765-4. Epub 2020 Mar 9. Nat Methods. 2020. PMID: 32152500 Review.
Predicting protein condensate formation using machine learning.
van Mierlo G, Jansen JRG, Wang J, Poser I, van Heeringen SJ, Vermeulen M. van Mierlo G, et al. Among authors: van heeringen sj. Cell Rep. 2021 Feb 2;34(5):108705. doi: 10.1016/j.celrep.2021.108705. Cell Rep. 2021. PMID: 33535034 Free article.
Off-the-shelf proximity biotinylation for interaction proteomics.
Santos-Barriopedro I, van Mierlo G, Vermeulen M. Santos-Barriopedro I, et al. Among authors: van mierlo g. Nat Commun. 2021 Aug 18;12(1):5015. doi: 10.1038/s41467-021-25338-4. Nat Commun. 2021. PMID: 34408139 Free PMC article.
Identification of Allobaculum mucolyticum as a novel human intestinal mucin degrader.
van Muijlwijk GH, van Mierlo G, Jansen PWTC, Vermeulen M, Bleumink-Pluym NMC, Palm NW, van Putten JPM, de Zoete MR. van Muijlwijk GH, et al. Among authors: van putten jpm, van mierlo g. Gut Microbes. 2021 Jan-Dec;13(1):1966278. doi: 10.1080/19490976.2021.1966278. Gut Microbes. 2021. PMID: 34455931 Free PMC article.
Off-the-shelf proximity biotinylation using ProtA-TurboID.
Santos-Barriopedro I, van Mierlo G, Vermeulen M. Santos-Barriopedro I, et al. Among authors: van mierlo g. Nat Protoc. 2023 Jan;18(1):36-57. doi: 10.1038/s41596-022-00748-w. Epub 2022 Oct 12. Nat Protoc. 2023. PMID: 36224470 Review.
105 results