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Page 1
Pre-Clinical Evaluation of the Hypomethylating Agent Decitabine for the Treatment of T-Cell Lymphoblastic Lymphoma.
Provez L, Putteman T, Landfors M, Roels J, Reunes L, T'Sas S, Van Loocke W, Lintermans B, De Coninck S, Thenoz M, Sleeckx W, Maćkowska-Maślak N, Taghon T, Mansour MR, Farah N, Norga K, Vandenberghe P, Kotecha RS, Goossens S, Degerman S, De Smedt R, Van Vlierberghe P. Provez L, et al. Among authors: van loocke w. Cancers (Basel). 2023 Jan 20;15(3):647. doi: 10.3390/cancers15030647. Cancers (Basel). 2023. PMID: 36765607 Free PMC article.
Targeting cytokine- and therapy-induced PIM1 activation in preclinical models of T-cell acute lymphoblastic leukemia and lymphoma.
De Smedt R, Morscio J, Reunes L, Roels J, Bardelli V, Lintermans B, Van Loocke W, Almeida A, Cheung LC, Kotecha RS, Mansour MR, Uyttebroeck A, Vandenberghe P, La Starza R, Mecucci C, Lammens T, Van Roy N, De Moerloose B, Barata JT, Taghon T, Goossens S, Van Vlierberghe P. De Smedt R, et al. Among authors: van loocke w, van roy n, van vlierberghe p. Blood. 2020 May 7;135(19):1685-1695. doi: 10.1182/blood.2019003880. Blood. 2020. PMID: 32315407 Free article.
Aging of preleukemic thymocytes drives CpG island hypermethylation in T-cell acute lymphoblastic leukemia.
Roels J, Thénoz M, Szarzyńska B, Landfors M, De Coninck S, Demoen L, Provez L, Kuchmiy A, Strubbe S, Reunes L, Pieters T, Matthijssens F, Van Loocke W, Erarslan-Uysal B, Richter-Pechańska P, Declerck K, Lammens T, De Moerloose B, Deforce D, Van Nieuwerburgh F, Cheung LC, Kotecha RS, Mansour MR, Ghesquière B, Van Camp G, Berghe WV, Kowalczyk JR, Szczepański T, Davé UP, Kulozik AE, Goossens S, Curtis DJ, Taghon T, Dawidowska M, Degerman S, Van Vlierberghe P. Roels J, et al. Among authors: van nieuwerburgh f, van loocke w, van vlierberghe p, van camp g. Blood Cancer Discov. 2020 Nov;1(3):274-289. doi: 10.1158/2643-3230.BCD-20-0059. Epub 2020 Sep 23. Blood Cancer Discov. 2020. PMID: 33179015 Free PMC article.
RUNX2 regulates leukemic cell metabolism and chemotaxis in high-risk T cell acute lymphoblastic leukemia.
Matthijssens F, Sharma ND, Nysus M, Nickl CK, Kang H, Perez DR, Lintermans B, Van Loocke W, Roels J, Peirs S, Demoen L, Pieters T, Reunes L, Lammens T, De Moerloose B, Van Nieuwerburgh F, Deforce DL, Cheung LC, Kotecha RS, Risseeuw MD, Van Calenbergh S, Takarada T, Yoneda Y, van Delft FW, Lock RB, Merkley SD, Chigaev A, Sklar LA, Mullighan CG, Loh ML, Winter SS, Hunger SP, Goossens S, Castillo EF, Ornatowski W, Van Vlierberghe P, Matlawska-Wasowska K. Matthijssens F, et al. Among authors: van delft fw, van nieuwerburgh f, van loocke w, van calenbergh s, van vlierberghe p. J Clin Invest. 2021 Mar 15;131(6):e141566. doi: 10.1172/JCI141566. J Clin Invest. 2021. PMID: 33555272 Free PMC article.
Cyclin D2 overexpression drives B1a-derived MCL-like lymphoma in mice.
Pieters T, T'Sas S, Vanhee S, Almeida A, Driege Y, Roels J, Van Loocke W, Daneels W, Baens M, Marchand A, Van Trimpont M, Matthijssens F, Morscio J, Lemeire K, Lintermans B, Reunes L, Chaltin P, Offner F, Van Dorpe J, Hochepied T, Berx G, Beyaert R, Staal J, Van Vlierberghe P, Goossens S. Pieters T, et al. Among authors: van dorpe j, van trimpont m, van loocke w, van vlierberghe p. J Exp Med. 2021 Oct 4;218(10):e20202280. doi: 10.1084/jem.20202280. Epub 2021 Aug 18. J Exp Med. 2021. PMID: 34406363 Free PMC article.
Genetic characterization and therapeutic targeting of MYC-rearranged T cell acute lymphoblastic leukaemia.
Milani G, Matthijssens F, Van Loocke W, Durinck K, Roels J, Peirs S, Thénoz M, Pieters T, Reunes L, Lintermans B, Vandamme N, Lammens T, Van Roy N, Van Nieuwerburgh F, Deforce D, Schwab C, Raimondi S, Dalla Pozza L, Carroll AJ 3rd, De Moerloose B, Benoit Y, Goossens S, Berx G, Harrison CJ, Basso G, Cavé H, Sutton R, Asnafi V, Meijerink J, Mullighan C, Loh M, Van Vlierberghe P. Milani G, et al. Among authors: van nieuwerburgh f, van loocke w, van roy n, van vlierberghe p. Br J Haematol. 2019 Apr;185(1):169-174. doi: 10.1111/bjh.15425. Epub 2018 Jun 25. Br J Haematol. 2019. PMID: 29938777 Free PMC article. No abstract available.
Novel biological insights in T-cell acute lymphoblastic leukemia.
Durinck K, Goossens S, Peirs S, Wallaert A, Van Loocke W, Matthijssens F, Pieters T, Milani G, Lammens T, Rondou P, Van Roy N, De Moerloose B, Benoit Y, Haigh J, Speleman F, Poppe B, Van Vlierberghe P. Durinck K, et al. Among authors: van loocke w, van roy n, van vlierberghe p. Exp Hematol. 2015 Aug;43(8):625-39. doi: 10.1016/j.exphem.2015.05.017. Epub 2015 Jun 26. Exp Hematol. 2015. PMID: 26123366 Free article. Review.
T-BET and EOMES Accelerate and Enhance Functional Differentiation of Human Natural Killer Cells.
Kiekens L, Van Loocke W, Taveirne S, Wahlen S, Persyn E, Van Ammel E, De Vos Z, Matthys P, Van Nieuwerburgh F, Taghon T, Van Vlierberghe P, Vandekerckhove B, Leclercq G. Kiekens L, et al. Among authors: van loocke w. Front Immunol. 2021 Sep 24;12:732511. doi: 10.3389/fimmu.2021.732511. eCollection 2021. Front Immunol. 2021. PMID: 34630413 Free PMC article.
TXNIP Promotes Human NK Cell Development but Is Dispensable for NK Cell Functionality.
Persyn E, Wahlen S, Kiekens L, Taveirne S, Van Loocke W, Van Ammel E, Van Nieuwerburgh F, Taghon T, Vandekerckhove B, Van Vlierberghe P, Leclercq G. Persyn E, et al. Among authors: van loocke w. Int J Mol Sci. 2022 Sep 26;23(19):11345. doi: 10.3390/ijms231911345. Int J Mol Sci. 2022. PMID: 36232644 Free PMC article.
37 results