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A Novel t(8;14)(q24;q11) Rearranged Human Cell Line as a Model for Mechanistic and Drug Discovery Studies of NOTCH1-Independent Human T-Cell Leukemia.
Tosello V, Milani G, Martines A, Macri N, Van Loocke W, Matthijssens F, Buldini B, Minuzzo S, Bongiovanni D, Schumacher RF, Amadori A, Van Vlierberghe P, Piovan E. Tosello V, et al. Among authors: van loocke w, van vlierberghe p. Cells. 2018 Oct 9;7(10):160. doi: 10.3390/cells7100160. Cells. 2018. PMID: 30304769 Free PMC article.
Targeting BET proteins improves the therapeutic efficacy of BCL-2 inhibition in T-cell acute lymphoblastic leukemia.
Peirs S, Frismantas V, Matthijssens F, Van Loocke W, Pieters T, Vandamme N, Lintermans B, Dobay MP, Berx G, Poppe B, Goossens S, Bornhauser BC, Bourquin JP, Van Vlierberghe P. Peirs S, et al. Among authors: van loocke w, van vlierberghe p. Leukemia. 2017 Oct;31(10):2037-2047. doi: 10.1038/leu.2017.10. Epub 2017 Jan 11. Leukemia. 2017. PMID: 28074072 Free article.
PRL3 enhances T-cell acute lymphoblastic leukemia growth through suppressing T-cell signaling pathways and apoptosis.
Garcia EG, Veloso A, Oliveira ML, Allen JR, Loontiens S, Brunson D, Do D, Yan C, Morris R, Iyer S, Garcia SP, Iftimia N, Van Loocke W, Matthijssens F, McCarthy K, Barata JT, Speleman F, Taghon T, Gutierrez A, Van Vlierberghe P, Haas W, Blackburn JS, Langenau DM. Garcia EG, et al. Among authors: van loocke w, van vlierberghe p. Leukemia. 2021 Mar;35(3):679-690. doi: 10.1038/s41375-020-0937-3. Epub 2020 Jun 30. Leukemia. 2021. PMID: 32606318 Free PMC article.
Long noncoding RNA signatures define oncogenic subtypes in T-cell acute lymphoblastic leukemia.
Wallaert A, Durinck K, Van Loocke W, Van de Walle I, Matthijssens F, Volders PJ, Avila Cobos F, Rombaut D, Rondou P, Mestdagh P, Vandesompele J, Poppe B, Taghon T, Soulier J, Van Vlierberghe P, Speleman F. Wallaert A, et al. Among authors: van de walle i, van loocke w, van vlierberghe p. Leukemia. 2016 Sep;30(9):1927-30. doi: 10.1038/leu.2016.82. Epub 2016 Apr 22. Leukemia. 2016. PMID: 27168467 No abstract available.
Characterization of the genome-wide TLX1 binding profile in T-cell acute lymphoblastic leukemia.
Durinck K, Van Loocke W, Van der Meulen J, Van de Walle I, Ongenaert M, Rondou P, Wallaert A, de Bock CE, Van Roy N, Poppe B, Cools J, Soulier J, Taghon T, Speleman F, Van Vlierberghe P. Durinck K, et al. Among authors: van der meulen j, van de walle i, van loocke w, van roy n, van vlierberghe p. Leukemia. 2015 Dec;29(12):2317-27. doi: 10.1038/leu.2015.162. Epub 2015 Jun 25. Leukemia. 2015. PMID: 26108691
Myb overexpression synergizes with the loss of Pten and is a dependency factor and therapeutic target in T-cell lymphoblastic leukemia.
Almeida A, T'Sas S, Pagliaro L, Fijalkowski I, Sleeckx W, Van Steenberge H, Zamponi R, Lintermans B, Van Loocke W, Palhais B, Reekmans A, Bardelli V, Demoen L, Reunes L, Deforce D, Van Nieuwerburgh F, Kentsis A, Ntziachristos P, Van Roy N, De Moerloose B, Mecucci C, La Starza R, Roti G, Goossens S, Van Vlierberghe P, Pieters T. Almeida A, et al. Among authors: van loocke w. Hemasphere. 2024 Mar 10;8(3):e51. doi: 10.1002/hem3.51. eCollection 2024 Mar. Hemasphere. 2024. PMID: 38463444 Free PMC article.
Human iPSC modeling recapitulates in vivo sympathoadrenal development and reveals an aberrant developmental subpopulation in familial neuroblastoma.
Van Haver S, Fan Y, Bekaert SL, Everaert C, Van Loocke W, Zanzani V, Deschildre J, Maestre IF, Amaro A, Vermeirssen V, De Preter K, Zhou T, Kentsis A, Studer L, Speleman F, Roberts SS. Van Haver S, et al. Among authors: van loocke w. iScience. 2023 Sep 30;27(1):108096. doi: 10.1016/j.isci.2023.108096. eCollection 2024 Jan 19. iScience. 2023. PMID: 38222111 Free PMC article.
SOX11 regulates SWI/SNF complex components as member of the adrenergic neuroblastoma core regulatory circuitry.
Decaesteker B, Louwagie A, Loontiens S, De Vloed F, Bekaert SL, Roels J, Vanhauwaert S, De Brouwer S, Sanders E, Berezovskaya A, Denecker G, D'haene E, Van Haver S, Van Loocke W, Van Dorpe J, Creytens D, Van Roy N, Pieters T, Van Neste C, Fischer M, Van Vlierberghe P, Roberts SS, Schulte J, Ek S, Versteeg R, Koster J, van Nes J, Zimmerman M, De Preter K, Speleman F. Decaesteker B, et al. Among authors: van loocke w. Nat Commun. 2023 Mar 7;14(1):1267. doi: 10.1038/s41467-023-36735-2. Nat Commun. 2023. PMID: 36882421 Free PMC article.
Pre-Clinical Evaluation of the Hypomethylating Agent Decitabine for the Treatment of T-Cell Lymphoblastic Lymphoma.
Provez L, Putteman T, Landfors M, Roels J, Reunes L, T'Sas S, Van Loocke W, Lintermans B, De Coninck S, Thenoz M, Sleeckx W, Maćkowska-Maślak N, Taghon T, Mansour MR, Farah N, Norga K, Vandenberghe P, Kotecha RS, Goossens S, Degerman S, De Smedt R, Van Vlierberghe P. Provez L, et al. Among authors: van loocke w. Cancers (Basel). 2023 Jan 20;15(3):647. doi: 10.3390/cancers15030647. Cancers (Basel). 2023. PMID: 36765607 Free PMC article.
IRF2 is required for development and functional maturation of human NK cells.
Persyn E, Wahlen S, Kiekens L, Van Loocke W, Siwe H, Van Ammel E, De Vos Z, Van Nieuwerburgh F, Matthys P, Taghon T, Vandekerckhove B, Van Vlierberghe P, Leclercq G. Persyn E, et al. Among authors: van loocke w. Front Immunol. 2022 Dec 5;13:1038821. doi: 10.3389/fimmu.2022.1038821. eCollection 2022. Front Immunol. 2022. PMID: 36544762 Free PMC article.
37 results