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IL-15-secreting CAR natural killer cells directed toward the pan-cancer target CD70 eliminate both cancer cells and cancer-associated fibroblasts.
Van den Eynde A, Gehrcken L, Verhezen T, Lau HW, Hermans C, Lambrechts H, Flieswasser T, Quatannens D, Roex G, Zwaenepoel K, Marcq E, Joye P, Cardenas De La Hoz E, Deben C, Gasparini A, Montay-Gruel P, Le Compte M, Lion E, Lardon F, Van Laere S, Siozopoulou V, Campillo-Davo D, De Waele J, Pauwels P, Jacobs J, Smits E, Van Audenaerde JRM. Van den Eynde A, et al. Among authors: van laere s. J Hematol Oncol. 2024 Feb 9;17(1):8. doi: 10.1186/s13045-024-01525-w. J Hematol Oncol. 2024. PMID: 38331849 Free PMC article.
Single-organoid analysis reveals clinically relevant treatment-resistant and invasive subclones in pancreatic cancer.
Le Compte M, De La Hoz EC, Peeters S, Fortes FR, Hermans C, Domen A, Smits E, Lardon F, Vandamme T, Lin A, Vanlanduit S, Roeyen G, Van Laere S, Prenen H, Peeters M, Deben C. Le Compte M, et al. Among authors: van laere s. NPJ Precis Oncol. 2023 Dec 8;7(1):128. doi: 10.1038/s41698-023-00480-y. NPJ Precis Oncol. 2023. PMID: 38066116 Free PMC article.
OrBITS: label-free and time-lapse monitoring of patient derived organoids for advanced drug screening.
Deben C, De La Hoz EC, Compte ML, Van Schil P, Hendriks JMH, Lauwers P, Yogeswaran SK, Lardon F, Pauwels P, Van Laere S, Bogaerts A, Smits E, Vanlanduit S, Lin A. Deben C, et al. Among authors: van schil p, van laere s. Cell Oncol (Dordr). 2023 Apr;46(2):299-314. doi: 10.1007/s13402-022-00750-0. Epub 2022 Dec 12. Cell Oncol (Dordr). 2023. PMID: 36508089 Free PMC article.
The role of adipose tissue and subsequent liver tissue hypoxia in obesity and early stage metabolic dysfunction associated steatotic liver disease.
Van Eyck A, Kwanten WJ, Peleman C, Makhout S, Van Laere S, Van De Maele K, Van Hoorenbeeck K, De Man J, De Winter BY, Francque S, Verhulst SL. Van Eyck A, et al. Among authors: van laere s. Int J Obes (Lond). 2024 Apr;48(4):512-522. doi: 10.1038/s41366-023-01443-w. Epub 2023 Dec 23. Int J Obes (Lond). 2024. PMID: 38142264
Mutational landscape of inflammatory breast cancer.
Bertucci F, Lerebours F, Ceccarelli M, Guille A, Syed N, Finetti P, Adélaïde J, Van Laere S, Goncalves A, Viens P, Birnbaum D, Mamessier E, Callens C, Bedognetti D. Bertucci F, et al. Among authors: van laere s. J Transl Med. 2024 Apr 18;22(1):374. doi: 10.1186/s12967-024-05198-4. J Transl Med. 2024. PMID: 38637846 Free PMC article.
Chitin-mediated blockade of chitinase-like proteins reduces tumor immunosuppression, inhibits lymphatic metastasis and enhances anti-PD-1 efficacy in complementary TNBC models.
Salembier R, De Haes C, Bellemans J, Demeyere K, Van Den Broeck W, Sanders NN, Van Laere S, Lyons TR, Meyer E, Steenbrugge J. Salembier R, et al. Among authors: van laere s. Breast Cancer Res. 2024 Apr 11;26(1):63. doi: 10.1186/s13058-024-01815-8. Breast Cancer Res. 2024. PMID: 38605414 Free PMC article.
XIAP overexpressing inflammatory breast cancer patients have high infiltration of immunosuppressive subsets and increased TNFR1 signaling targetable with Birinapant.
Van Berckelaer C, Van Laere S, Lee S, Morse MA, Geradts J, Dirix L, Kockx M, Bertucci F, Van Dam P, Devi GR. Van Berckelaer C, et al. Among authors: van laere s. Transl Oncol. 2024 May;43:101907. doi: 10.1016/j.tranon.2024.101907. Epub 2024 Feb 27. Transl Oncol. 2024. PMID: 38412664 Free PMC article.
Correction: Maternal Embryonic Leucine Zipper Kinase Is Associated with Metastasis in Triple-negative Breast Cancer.
Xie X, Chauhan GB, Edupuganti R, Kogawa T, Park J, Tacam M, Tan AW, Mughees M, Vidhu F, Liu DD, Taliaferro JM, Pitner MK, Browning LS, Lee JH, Bertucci F, Shen Y, Wang J, Ueno NT, Krishnamurthy S, Hortobagyi GN, Tripathy D, Van Laere SJ, Bartholomeusz G, Dalby KN, Bartholomeusz C. Xie X, et al. Among authors: van laere sj. Cancer Res Commun. 2024 Jan 29;4(1):236. doi: 10.1158/2767-9764.CRC-24-0046. Cancer Res Commun. 2024. PMID: 38282551 Free PMC article. No abstract available.
253 results