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mRNA-LNP vaccines tuned for systemic immunization induce strong antitumor immunity by engaging splenic immune cells.
Mol Ther. 2022 Sep 7;30(9):3078-3094. doi: 10.1016/j.ymthe.2022.07.007. Epub 2022 Jul 12.
Mol Ther. 2022.
PMID: 35821637
Free PMC article.
VHH antibody targeting the chemokine receptor CX3CR1 inhibits progression of atherosclerosis.
Low S, Wu H, Jerath K, Tibolla A, Fogal B, Conrad R, MacDougall M, Kerr S, Berger V, Dave R, Villalona J, Pantages L, Ahlberg J, Li H, Van Hoorick D, Ververken C, Broadwater J, Waterman A, Singh S, Kroe-Barrett R.
Low S, et al. Among authors: van hoorick d.
MAbs. 2020 Jan-Dec;12(1):1709322. doi: 10.1080/19420862.2019.1709322.
MAbs. 2020.
PMID: 31924119
Free PMC article.
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The constitutive activity of the virally encoded chemokine receptor US28 accelerates glioblastoma growth.
Heukers R, Fan TS, de Wit RH, van Senten JR, De Groof TWM, Bebelman MP, Lagerweij T, Vieira J, de Munnik SM, Smits-de Vries L, van Offenbeek J, Rahbar A, van Hoorick D, Söderberg-Naucler C, Würdinger T, Leurs R, Siderius M, Vischer HF, Smit MJ.
Heukers R, et al. Among authors: van hoorick d.
Oncogene. 2018 Jul;37(30):4110-4121. doi: 10.1038/s41388-018-0255-7. Epub 2018 Apr 30.
Oncogene. 2018.
PMID: 29706656
Free PMC article.
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Modulating ion channel function with antibodies and nanobodies.
Stortelers C, Pinto-Espinoza C, Van Hoorick D, Koch-Nolte F.
Stortelers C, et al. Among authors: van hoorick d.
Curr Opin Immunol. 2018 Jun;52:18-26. doi: 10.1016/j.coi.2018.02.003. Epub 2018 Mar 23.
Curr Opin Immunol. 2018.
PMID: 29579624
Review.
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Kv channel gating requires a compatible S4-S5 linker and bottom part of S6, constrained by non-interacting residues.
Labro AJ, Raes AL, Grottesi A, Van Hoorick D, Sansom MS, Snyders DJ.
Labro AJ, et al. Among authors: van hoorick d.
J Gen Physiol. 2008 Dec;132(6):667-80. doi: 10.1085/jgp.200810048.
J Gen Physiol. 2008.
PMID: 19029374
Free PMC article.
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The aromatic cluster in KCHIP1b affects Kv4 inactivation gating.
Van Hoorick D, Raes A, Snyders DJ.
Van Hoorick D, et al.
J Physiol. 2007 Sep 15;583(Pt 3):959-69. doi: 10.1113/jphysiol.2007.139550. Epub 2007 Jul 19.
J Physiol. 2007.
PMID: 17640927
Free PMC article.
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Differential modulation of Kv4 kinetics by KCHIP1 splice variants.
Van Hoorick D, Raes A, Keysers W, Mayeur E, Snyders DJ.
Van Hoorick D, et al.
Mol Cell Neurosci. 2003 Oct;24(2):357-66. doi: 10.1016/s1044-7431(03)00174-x.
Mol Cell Neurosci. 2003.
PMID: 14572458
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Obligatory heterotetramerization of three previously uncharacterized Kv channel alpha-subunits identified in the human genome.
Ottschytsch N, Raes A, Van Hoorick D, Snyders DJ.
Ottschytsch N, et al. Among authors: van hoorick d.
Proc Natl Acad Sci U S A. 2002 Jun 11;99(12):7986-91. doi: 10.1073/pnas.122617999.
Proc Natl Acad Sci U S A. 2002.
PMID: 12060745
Free PMC article.
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