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In Vitro Evaluation of Poly(lactide-co-glycolide) In Situ Forming Gels for Bedaquiline Fumarate Salt and Pharmacokinetics Following Subcutaneous Injection in Rats.
Pharmaceutics. 2021 Aug 10;13(8):1231. doi: 10.3390/pharmaceutics13081231.
Pharmaceutics. 2021.
PMID: 34452192
Free PMC article.
Preclinical Bioavailability Strategy for Decisions on Clinical Drug Formulation Development: An In Depth Analysis.
Van den Bergh A, Van Hemelryck S, Bevernage J, Van Peer A, Brewster M, Mackie C, Mannaert E.
Van den Bergh A, et al. Among authors: van hemelryck s.
Mol Pharm. 2018 Jul 2;15(7):2633-2645. doi: 10.1021/acs.molpharmaceut.8b00172. Epub 2018 Jun 11.
Mol Pharm. 2018.
PMID: 29799758
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In vivo models and decision trees for formulation development in early drug development: A review of current practices and recommendations for biopharmaceutical development.
Zane P, Gieschen H, Kersten E, Mathias N, Ollier C, Johansson P, Van den Bergh A, Van Hemelryck S, Reichel A, Rotgeri A, Schäfer K, Müllertz A, Langguth P.
Zane P, et al. Among authors: van hemelryck s.
Eur J Pharm Biopharm. 2019 Sep;142:222-231. doi: 10.1016/j.ejpb.2019.06.010. Epub 2019 Jun 21.
Eur J Pharm Biopharm. 2019.
PMID: 31233862
Review.
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Clinical pharmacokinetics, pharmacodynamics, safety, and tolerability of JNJ-54175446, a brain permeable P2X7 antagonist, in a randomised single-ascending dose study in healthy participants.
Timmers M, Ravenstijn P, Xi L, Triana-Baltzer G, Furey M, Van Hemelryck S, Biewenga J, Ceusters M, Bhattacharya A, van den Boer M, van Nueten L, de Boer P.
Timmers M, et al. Among authors: van hemelryck s.
J Psychopharmacol. 2018 Dec;32(12):1341-1350. doi: 10.1177/0269881118800067. Epub 2018 Sep 27.
J Psychopharmacol. 2018.
PMID: 30260294
Clinical Trial.
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Bioequivalence of a Pediatric Fixed-Dose Combination Tablet Darunavir/Cobicistat/Emtricitabine/Tenofovir Alafenamide Compared With Coadministration of the Separate Agents in Healthy Adults: An Open-Label, Randomized, Replicate Crossover Study.
Van Hemelryck S, Van Landuyt E, Ariyawansa J, Vanveggel S, Palmer M.
Van Hemelryck S, et al.
Clin Pharmacol Drug Dev. 2023 Nov;12(11):1060-1068. doi: 10.1002/cpdd.1293. Epub 2023 Jun 19.
Clin Pharmacol Drug Dev. 2023.
PMID: 37335552
Clinical Trial.
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Volatile analysis of spoiled, artisan-type, modified-atmosphere-packaged cooked ham stored under different temperatures.
Leroy F, Vasilopoulos C, Van Hemelryck S, Falony G, De Vuyst L.
Leroy F, et al. Among authors: van hemelryck s.
Food Microbiol. 2009 Feb;26(1):94-102. doi: 10.1016/j.fm.2008.08.005. Epub 2008 Oct 17.
Food Microbiol. 2009.
PMID: 19028312
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Determining orthogonal chromatographic systems prior to the development of methods to characterise impurities in drug substances.
Van Gyseghem E, Van Hemelryck S, Daszykowski M, Questier F, Massart DL, Vander Heyden Y.
Van Gyseghem E, et al. Among authors: van hemelryck s.
J Chromatogr A. 2003 Feb 21;988(1):77-93. doi: 10.1016/s0021-9673(02)02012-5.
J Chromatogr A. 2003.
PMID: 12647823
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