Van Haandel L - Search Results

1

Novel Protective Role of Nicotinamide Phosphoribosyltransferase in Acetaminophen-Induced Acute Liver Injury in Mice.

Zhang LQ, Nsumu M, Huang P, Heruth DP, Riordan SM, Shortt K, Zhang N, Grigoryev DN, Li DY, Friesen CA, Van Haandel L, Leeder JS, Olson J, Ye SQ. Zhang LQ, et al. Among authors: van haandel l. Am J Pathol. 2018 Jul;188(7):1640-1652. doi: 10.1016/j.ajpath.2018.04.004. Epub 2018 Apr 22. Am J Pathol. 2018. PMID: 29684358 Free PMC article.

2

Metabolic and molecular insights into an essential role of nicotinamide phosphoribosyltransferase.

Zhang LQ, Van Haandel L, Xiong M, Huang P, Heruth DP, Bi C, Gaedigk R, Jiang X, Li DY, Wyckoff G, Grigoryev DN, Gao L, Li L, Wu M, Leeder JS, Ye SQ. Zhang LQ, et al. Among authors: van haandel l. Cell Death Dis. 2017 Mar 23;8(3):e2705. doi: 10.1038/cddis.2017.132. Cell Death Dis. 2017. PMID: 28333140 Free PMC article.

3

Nicotinamide Phosphoribosyltransferase Deficiency Potentiates the Antiproliferative Activity of Methotrexate through Enhanced Depletion of Intracellular ATP.

Singh RK, van Haandel L, Heruth DP, Ye SQ, Leeder JS, Becker ML, Funk RS. Singh RK, et al. Among authors: van haandel l. J Pharmacol Exp Ther. 2018 Apr;365(1):96-106. doi: 10.1124/jpet.117.246199. Epub 2018 Feb 2. J Pharmacol Exp Ther. 2018. PMID: 29420256 Free PMC article.

4

Intensive and prolonged urine collection in preterm infants reveals three distinct indomethacin metabolic patterns: potential implications for drug dosing.

Lewis T, Van Haandel L, Scott A, Leeder JS. Lewis T, et al. Among authors: van haandel l. Pediatr Res. 2018 Sep;84(3):325-327. doi: 10.1038/s41390-018-0051-7. Epub 2018 Jul 2. Pediatr Res. 2018. PMID: 29967531 Free PMC article. No abstract available.

5

Low-dose methotrexate results in the selective accumulation of aminoimidazole carboxamide ribotide in an erythroblastoid cell line.

Funk RS, van Haandel L, Becker ML, Leeder JS. Funk RS, et al. Among authors: van haandel l. J Pharmacol Exp Ther. 2013 Oct;347(1):154-63. doi: 10.1124/jpet.113.206672. Epub 2013 Jul 25. J Pharmacol Exp Ther. 2013. PMID: 23887097 Free PMC article.

6

Urinary biomarkers of trimethoprim bioactivation in vivo following therapeutic dosing in children.

van Haandel L, Goldman JL, Pearce RE, Leeder JS. van Haandel L, et al. Chem Res Toxicol. 2014 Feb 17;27(2):211-8. doi: 10.1021/tx4003325. Epub 2014 Jan 13. Chem Res Toxicol. 2014. PMID: 24380396 Clinical Trial.

7

Folate depletion and increased glutamation in juvenile idiopathic arthritis patients treated with methotrexate.

Funk RS, van Haandel L, Leeder JS, Becker ML. Funk RS, et al. Among authors: van haandel l. Arthritis Rheumatol. 2014 Dec;66(12):3476-85. doi: 10.1002/art.38865. Arthritis Rheumatol. 2014. PMID: 25186097 Free PMC article.

8

In Vitro Hepatic Oxidative Biotransformation of Trimethoprim.

Goldman JL, Leeder JS, Van Haandel L, Pearce RE. Goldman JL, et al. Among authors: van haandel l. Drug Metab Dispos. 2015 Sep;43(9):1372-80. doi: 10.1124/dmd.115.065193. Epub 2015 Jul 2. Drug Metab Dispos. 2015. PMID: 26138612 Free PMC article.

9

Quantification of pravastatin acid, lactone and isomers in human plasma by UHPLC-MS/MS and its application to a pediatric pharmacokinetic study.

van Haandel L, Gibson KT, Leeder JS, Wagner JB. van Haandel L, et al. J Chromatogr B Analyt Technol Biomed Life Sci. 2016 Feb 15;1012-1013:169-77. doi: 10.1016/j.jchromb.2016.01.038. Epub 2016 Jan 24. J Chromatogr B Analyt Technol Biomed Life Sci. 2016. PMID: 26849185

10

Measurement of methotrexate polyglutamates in human erythrocytes by ion-pair UPLC-MS/MS.

van Haandel L, Becker ML, Williams TD, Leeder JS, Stobaugh JF. van Haandel L, et al. Bioanalysis. 2011 Dec;3(24):2783-96. doi: 10.4155/bio.11.288. Bioanalysis. 2011. PMID: 22185278

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