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High expression of secretory leukocyte protease inhibitor (SLPI) in stage III micro-satellite stable colorectal cancer is associated with reduced disease recurrence.
Nugteren S, den Uil SH, Delis-van Diemen PM, Simons-Oosterhuis Y, Lindenbergh-Kortleve DJ, van Haaften DH, Stockmann HBAC, Sanders J, Meijer GA, Fijneman RJA, Samsom JN. Nugteren S, et al. Among authors: van haaften dh. Sci Rep. 2022 Jul 16;12(1):12174. doi: 10.1038/s41598-022-16427-5. Sci Rep. 2022. PMID: 35842496 Free PMC article.
Expression of the immune modulator secretory leukocyte protease inhibitor (SLPI) in colorectal cancer liver metastases and matched primary tumors is associated with a poorer prognosis.
Nugteren S, Goos JACM, Delis-van Diemen PM, Simons-Oosterhuis Y, Lindenbergh-Kortleve DJ, van Haaften DH, Sanders J, Meijer GA, Fijneman RJA, Samsom JN. Nugteren S, et al. Among authors: van haaften dh. Oncoimmunology. 2020 Oct 13;9(1):1832761. doi: 10.1080/2162402X.2020.1832761. Oncoimmunology. 2020. PMID: 33101778 Free PMC article.
IL-10 signaling prevents gluten-dependent intraepithelial CD4+ cytotoxic T lymphocyte infiltration and epithelial damage in the small intestine.
Costes LMM, Lindenbergh-Kortleve DJ, van Berkel LA, Veenbergen S, Raatgeep HRC, Simons-Oosterhuis Y, van Haaften DH, Karrich JJ, Escher JC, Groeneweg M, Clausen BE, Cupedo T, Samsom JN. Costes LMM, et al. Among authors: van haaften dh. Mucosal Immunol. 2019 Mar;12(2):479-490. doi: 10.1038/s41385-018-0118-0. Epub 2018 Dec 12. Mucosal Immunol. 2019. PMID: 30542112 Free article.