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Unravelling the pharmacokinetics of aflatoxin B1: In vitro determination of Michaelis-Menten constants, intrinsic clearance and the metabolic contribution of CYP1A2 and CYP3A4 in pooled human liver microsomes.
Lootens O, De Boevre M, Gasthuys E, Van Bocxlaer J, Vermeulen A, De Saeger S. Lootens O, et al. Among authors: van bocxlaer j. Front Microbiol. 2022 Aug 29;13:988083. doi: 10.3389/fmicb.2022.988083. eCollection 2022. Front Microbiol. 2022. PMID: 36110298 Free PMC article.
The mycotoxin T-2 inhibits hepatic cytochrome P4503A activity in pigs.
Goossens J, De Bock L, Osselaere A, Verbrugghe E, Devreese M, Boussery K, Van Bocxlaer J, De Backer P, Croubels S. Goossens J, et al. Among authors: van bocxlaer j. Food Chem Toxicol. 2013 Jul;57:54-6. doi: 10.1016/j.fct.2013.03.009. Epub 2013 Mar 21. Food Chem Toxicol. 2013. PMID: 23524315
The Ontogeny of Cytochrome P450 Enzyme Activity and Protein Abundance in Conventional Pigs in Support of Preclinical Pediatric Drug Research.
Millecam J, De Clerck L, Govaert E, Devreese M, Gasthuys E, Schelstraete W, Deforce D, De Bock L, Van Bocxlaer J, Sys S, Croubels S. Millecam J, et al. Among authors: van bocxlaer j. Front Pharmacol. 2018 May 14;9:470. doi: 10.3389/fphar.2018.00470. eCollection 2018. Front Pharmacol. 2018. PMID: 29867477 Free PMC article.
155 results