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Increased Ca2+ Transient Underlies RyR2-Related Left Ventricular Noncompaction.
Ni M, Li Y, Wei J, Song Z, Wang H, Yao J, Chen YX, Belke D, Estillore JP, Wang R, Vallmitjana A, Benitez R, Hove-Madsen L, Feng W, Chen J, Roston TM, Sanatani S, Lehman A, Chen SRW. Ni M, et al. Among authors: vallmitjana a. Circ Res. 2023 Jul 7;133(2):177-192. doi: 10.1161/CIRCRESAHA.123.322504. Epub 2023 Jun 16. Circ Res. 2023. PMID: 37325910
Phospholamban knockout breaks arrhythmogenic Ca²⁺ waves and suppresses catecholaminergic polymorphic ventricular tachycardia in mice.
Bai Y, Jones PP, Guo J, Zhong X, Clark RB, Zhou Q, Wang R, Vallmitjana A, Benitez R, Hove-Madsen L, Semeniuk L, Guo A, Song LS, Duff HJ, Chen SR. Bai Y, et al. Among authors: vallmitjana a. Circ Res. 2013 Aug 16;113(5):517-26. doi: 10.1161/CIRCRESAHA.113.301678. Epub 2013 Jul 15. Circ Res. 2013. PMID: 23856523 Free PMC article.
Ca2+-CaM Dependent Inactivation of RyR2 Underlies Ca2+ Alternans in Intact Heart.
Wei J, Yao J, Belke D, Guo W, Zhong X, Sun B, Wang R, Paul Estillore J, Vallmitjana A, Benitez R, Hove-Madsen L, Alvarez-Lacalle E, Echebarria B, Chen SRW. Wei J, et al. Among authors: vallmitjana a. Circ Res. 2021 Feb 19;128(4):e63-e83. doi: 10.1161/CIRCRESAHA.120.318429. Epub 2020 Dec 30. Circ Res. 2021. PMID: 33375811 Free article.
Reduced expression of cardiac ryanodine receptor protects against stress-induced ventricular tachyarrhythmia, but increases the susceptibility to cardiac alternans.
Zhong X, Vallmitjana A, Sun B, Xiao Z, Guo W, Wei J, Ni M, Chen Y, O'Brien ER, Gillis AM, Hoshijima M, Takeshima H, Hove-Madsen L, Benitez R, Belke D, Wayne Chen SR. Zhong X, et al. Among authors: vallmitjana a. Biochem J. 2018 Jan 5;475(1):169-183. doi: 10.1042/BCJ20170631. Biochem J. 2018. PMID: 29170159
Cardiac ryanodine receptor calcium release deficiency syndrome.
Sun B, Yao J, Ni M, Wei J, Zhong X, Guo W, Zhang L, Wang R, Belke D, Chen YX, Lieve KVV, Broendberg AK, Roston TM, Blankoff I, Kammeraad JA, von Alvensleben JC, Lazarte J, Vallmitjana A, Bohne LJ, Rose RA, Benitez R, Hove-Madsen L, Napolitano C, Hegele RA, Fill M, Sanatani S, Wilde AAM, Roberts JD, Priori SG, Jensen HK, Chen SRW. Sun B, et al. Among authors: vallmitjana a. Sci Transl Med. 2021 Feb 3;13(579):eaba7287. doi: 10.1126/scitranslmed.aba7287. Sci Transl Med. 2021. PMID: 33536282 Free article.
32 results