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Page 1
The origin of intestinal cancer in the context of inflammation.
Verhagen MP, Joosten R, Schmitt M, Valimaki N, Sacchetti A, Rajamaki K, Choi J, Procopio P, Silva S, van der Steen B, van den Bosch TPP, Seinstra D, Doukas M, Augenlicht LH, Aaltonen LA, Fodde R. Verhagen MP, et al. Among authors: valimaki n. bioRxiv [Preprint]. 2023 Nov 1:2023.10.02.560432. doi: 10.1101/2023.10.02.560432. bioRxiv. 2023. PMID: 37873142 Free PMC article. Preprint.
The Contribution of Genetic Variation of Streptococcus pneumoniae to the Clinical Manifestation of Invasive Pneumococcal Disease.
Cremers AJH, Mobegi FM, van der Gaast-de Jongh C, van Weert M, van Opzeeland FJ, Vehkala M, Knol MJ, Bootsma HJ, Välimäki N, Croucher NJ, Meis JF, Bentley S, van Hijum SAFT, Corander J, Zomer AL, Ferwerda G, de Jonge MI. Cremers AJH, et al. Among authors: valimaki n. Clin Infect Dis. 2019 Jan 1;68(1):61-69. doi: 10.1093/cid/ciy417. Clin Infect Dis. 2019. PMID: 29788414
Genetic and Epigenetic Characteristics of Inflammatory Bowel Disease-Associated Colorectal Cancer.
Rajamäki K, Taira A, Katainen R, Välimäki N, Kuosmanen A, Plaketti RM, Seppälä TT, Ahtiainen M, Wirta EV, Vartiainen E, Sulo P, Ravantti J, Lehtipuro S, Granberg KJ, Nykter M, Tanskanen T, Ristimäki A, Koskensalo S, Renkonen-Sinisalo L, Lepistö A, Böhm J, Taipale J, Mecklin JP, Aavikko M, Palin K, Aaltonen LA. Rajamäki K, et al. Among authors: valimaki n. Gastroenterology. 2021 Aug;161(2):592-607. doi: 10.1053/j.gastro.2021.04.042. Epub 2021 Apr 27. Gastroenterology. 2021. PMID: 33930428 Free article.
Vitamin C boosts DNA demethylation in TET2 germline mutation carriers.
Taira A, Palin K, Kuosmanen A, Välimäki N, Kuittinen O, Kuismin O, Kaasinen E, Rajamäki K, Aaltonen LA. Taira A, et al. Among authors: valimaki n. Clin Epigenetics. 2023 Jan 14;15(1):7. doi: 10.1186/s13148-022-01404-6. Clin Epigenetics. 2023. PMID: 36639817 Free PMC article. Clinical Trial.
Paneth cells as the origin of intestinal cancer in the context of inflammation.
Verhagen MP, Joosten R, Schmitt M, Sacchetti A, Choi J, Välimäki N, Aaltonen LA, Augenlicht LH, Fodde R. Verhagen MP, et al. Among authors: valimaki n. Res Sq [Preprint]. 2023 Jan 19:rs.3.rs-2458794. doi: 10.21203/rs.3.rs-2458794/v1. Res Sq. 2023. PMID: 36711533 Free PMC article. Preprint.
Whole-Genome Sequencing of Growth Hormone (GH)-Secreting Pituitary Adenomas.
Välimäki N, Demir H, Pitkänen E, Kaasinen E, Karppinen A, Kivipelto L, Schalin-Jäntti C, Aaltonen LA, Karhu A. Välimäki N, et al. J Clin Endocrinol Metab. 2015 Oct;100(10):3918-27. doi: 10.1210/jc.2015-3129. Epub 2015 Aug 17. J Clin Endocrinol Metab. 2015. PMID: 26280510
Retrotransposon insertions can initiate colorectal cancer and are associated with poor survival.
Cajuso T, Sulo P, Tanskanen T, Katainen R, Taira A, Hänninen UA, Kondelin J, Forsström L, Välimäki N, Aavikko M, Kaasinen E, Ristimäki A, Koskensalo S, Lepistö A, Renkonen-Sinisalo L, Seppälä T, Kuopio T, Böhm J, Mecklin JP, Kilpivaara O, Pitkänen E, Palin K, Aaltonen LA. Cajuso T, et al. Among authors: valimaki n. Nat Commun. 2019 Sep 6;10(1):4022. doi: 10.1038/s41467-019-11770-0. Nat Commun. 2019. PMID: 31492840 Free PMC article.
No evidence of EMAST in whole genome sequencing data from 248 colorectal cancers.
Kondelin J, Martin S, Katainen R, Renkonen-Sinisalo L, Lepistö A, Koskensalo S, Böhm J, Mecklin JP, Cajuso T, Hänninen UA, Välimäki N, Ravantti J, Rajamäki K, Palin K, Aaltonen LA. Kondelin J, et al. Among authors: valimaki n. Genes Chromosomes Cancer. 2021 Jul;60(7):463-473. doi: 10.1002/gcc.22941. Epub 2021 Feb 19. Genes Chromosomes Cancer. 2021. PMID: 33527622
Deficient H2A.Z deposition is associated with genesis of uterine leiomyoma.
Berta DG, Kuisma H, Välimäki N, Räisänen M, Jäntti M, Pasanen A, Karhu A, Kaukomaa J, Taira A, Cajuso T, Nieminen S, Penttinen RM, Ahonen S, Lehtonen R, Mehine M, Vahteristo P, Jalkanen J, Sahu B, Ravantti J, Mäkinen N, Rajamäki K, Palin K, Taipale J, Heikinheimo O, Bützow R, Kaasinen E, Aaltonen LA. Berta DG, et al. Among authors: valimaki n. Nature. 2021 Aug;596(7872):398-403. doi: 10.1038/s41586-021-03747-1. Epub 2021 Aug 4. Nature. 2021. PMID: 34349258
59 results