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The striatal kinase DCLK3 produces neuroprotection against mutant huntingtin.
Galvan L, Francelle L, Gaillard MC, de Longprez L, Carrillo-de Sauvage MA, Liot G, Cambon K, Stimmer L, Luccantoni S, Flament J, Valette J, de Chaldée M, Auregan G, Guillermier M, Joséphine C, Petit F, Jan C, Jarrige M, Dufour N, Bonvento G, Humbert S, Saudou F, Hantraye P, Merienne K, Bemelmans AP, Perrier AL, Déglon N, Brouillet E. Galvan L, et al. Among authors: valette j. Brain. 2018 May 1;141(5):1434-1454. doi: 10.1093/brain/awy057. Brain. 2018. PMID: 29534157 Free PMC article.
Multimodal neuroimaging provides a highly consistent picture of energy metabolism, validating 31P MRS for measuring brain ATP synthesis.
Chaumeil MM, Valette J, Guillermier M, Brouillet E, Boumezbeur F, Herard AS, Bloch G, Hantraye P, Lebon V. Chaumeil MM, et al. Among authors: valette j. Proc Natl Acad Sci U S A. 2009 Mar 10;106(10):3988-93. doi: 10.1073/pnas.0806516106. Epub 2009 Feb 20. Proc Natl Acad Sci U S A. 2009. PMID: 19234118 Free PMC article.
pH as a biomarker of neurodegeneration in Huntington's disease: a translational rodent-human MRS study.
Chaumeil MM, Valette J, Baligand C, Brouillet E, Hantraye P, Bloch G, Gaura V, Rialland A, Krystkowiak P, Verny C, Damier P, Remy P, Bachoud-Levi AC, Carlier P, Lebon V. Chaumeil MM, et al. Among authors: valette j. J Cereb Blood Flow Metab. 2012 May;32(5):771-9. doi: 10.1038/jcbfm.2012.15. Epub 2012 Feb 29. J Cereb Blood Flow Metab. 2012. PMID: 22373643 Free PMC article.
150 results