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Apaf-1 inhibitors protect from unwanted cell death in in vivo models of kidney ischemia and chemotherapy induced ototoxicity.
Orzáez M, Sancho M, Marchán S, Mondragón L, Montava R, Valero JG, Landeta O, Basañez G, Carbajo RJ, Pineda-Lucena A, Bujons J, Moure A, Messeguer A, Lagunas C, Herrero C, Pérez-Payá E. Orzáez M, et al. Among authors: valero jg. PLoS One. 2014 Oct 20;9(10):e110979. doi: 10.1371/journal.pone.0110979. eCollection 2014. PLoS One. 2014. PMID: 25330150 Free PMC article.
Patient-derived follicular lymphoma spheroids recapitulate lymph node signaling and immune profile uncovering galectin-9 as a novel immunotherapeutic target.
Dobaño-López C, Valero JG, Araujo-Ayala F, Nadeu F, Gava F, Faria C, Norlund M, Morin R, Bernes-Lasserre P, Arenas F, Grau M, López C, López-Oreja I, Serrat N, Martínez-Farran A, Hernández L, Playa-Albinyana H, Giménez R, Beà S, Campo E, Lagarde JM, López-Guillermo A, Magnano L, Colomer D, Bezombes C, Pérez-Galán P. Dobaño-López C, et al. Among authors: valero jg. Blood Cancer J. 2024 May 2;14(1):75. doi: 10.1038/s41408-024-01041-7. Blood Cancer J. 2024. PMID: 38697976 Free article.
Patient-derived lymphoma spheroids integrating immune tumor microenvironment as preclinical follicular lymphoma models for personalized medicine.
Faria C, Gava F, Gravelle P, Valero JG, Dobaño-López C, Van Acker N, Quelen C, Jalowicki G, Morin R, Rossi C, Lagarde JM, Fournié JJ, Ysebaert L, Laurent C, Pérez-Galán P, Bezombes C. Faria C, et al. Among authors: valero jg. J Immunother Cancer. 2023 Oct;11(10):e007156. doi: 10.1136/jitc-2023-007156. J Immunother Cancer. 2023. PMID: 37899130 Free PMC article.
A novel patient-derived 3D model recapitulates mantle cell lymphoma lymph node signaling, immune profile and in vivo ibrutinib responses.
Araujo-Ayala F, Dobaño-López C, Valero JG, Nadeu F, Gava F, Faria C, Norlund M, Morin R, Bernes-Lasserre P, Serrat N, Playa-Albinyana H, Giménez R, Campo E, Lagarde JM, López-Guillermo A, Gine E, Colomer D, Bezombes C, Pérez-Galán P. Araujo-Ayala F, et al. Among authors: valero jg. Leukemia. 2023 Jun;37(6):1311-1323. doi: 10.1038/s41375-023-01885-1. Epub 2023 Apr 8. Leukemia. 2023. PMID: 37031299 Free PMC article.
Venetoclax improves CD20 immunotherapy in a mouse model of MYC/BCL2 double-expressor diffuse large B-cell lymphoma.
Melchor J, Garcia-Lacarte M, Grijalba SC, Arnaiz-Leché A, Pascual M, Panizo C, Blanco O, Segura V, Novo FJ, Valero JG, Pérez-Galán P, Martinez-Climent JA, Roa S. Melchor J, et al. Among authors: valero jg. J Immunother Cancer. 2023 Feb;11(2):e006113. doi: 10.1136/jitc-2022-006113. J Immunother Cancer. 2023. PMID: 36854569 Free PMC article.
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