Valentine MT - Search Results

1

Discovery of 4'-[(imidazol-1-yl)methyl]biphenyl-2-sulfonamides as dual endothelin/angiotensin II receptor antagonists.

Tellew JE, Baska RA, Beyer SM, Carlson KE, Cornelius LA, Fadnis L, Gu Z, Kunst BL, Kowala MC, Monshizadegan H, Murugesan N, Ryan CS, Valentine MT, Yang Y, Macor JE. Tellew JE, et al. Among authors: valentine mt. Bioorg Med Chem Lett. 2003 Mar 24;13(6):1093-6. doi: 10.1016/s0960-894x(03)00018-0. Bioorg Med Chem Lett. 2003. PMID: 12643919

2

Discovery of N-isoxazolyl biphenylsulfonamides as potent dual angiotensin II and endothelin A receptor antagonists.

Murugesan N, Tellew JE, Gu Z, Kunst BL, Fadnis L, Cornelius LA, Baska RA, Yang Y, Beyer SM, Monshizadegan H, Dickinson KE, Panchal B, Valentine MT, Chong S, Morrison RA, Carlson KE, Powell JR, Moreland S, Barrish JC, Kowala MC, Macor JE. Murugesan N, et al. Among authors: valentine mt. J Med Chem. 2002 Aug 29;45(18):3829-35. doi: 10.1021/jm020138n. J Med Chem. 2002. PMID: 12190306

3

Dual angiotensin II and endothelin A receptor antagonists: synthesis of 2'-substituted N-3-isoxazolyl biphenylsulfonamides with improved potency and pharmacokinetics.

Murugesan N, Gu Z, Fadnis L, Tellew JE, Baska RA, Yang Y, Beyer SM, Monshizadegan H, Dickinson KE, Valentine MT, Humphreys WG, Lan SJ, Ewing WR, Carlson KE, Kowala MC, Zahler R, Macor JE. Murugesan N, et al. Among authors: valentine mt. J Med Chem. 2005 Jan 13;48(1):171-9. doi: 10.1021/jm049548x. J Med Chem. 2005. PMID: 15634011

4

Prospective identification of biologically active structures by topomer shape similarity searching.

Cramer RD, Poss MA, Hermsmeier MA, Caulfield TJ, Kowala MC, Valentine MT. Cramer RD, et al. Among authors: valentine mt. J Med Chem. 1999 Sep 23;42(19):3919-33. doi: 10.1021/jm990159q. J Med Chem. 1999. PMID: 10508440

5

Selective blockade of the endothelin subtype A receptor decreases early atherosclerosis in hamsters fed cholesterol.

Kowala MC, Rose PM, Stein PD, Goller N, Recce R, Beyer S, Valentine M, Barton D, Durham SK. Kowala MC, et al. Am J Pathol. 1995 Apr;146(4):819-26. Am J Pathol. 1995. PMID: 7717449 Free PMC article.

6

Characterization of atherosclerosis in LDL receptor knockout mice: macrophage accumulation correlates with rapid and sustained expression of aortic MCP-1/JE.

Kowala MC, Recce R, Beyer S, Gu C, Valentine M. Kowala MC, et al. Atherosclerosis. 2000 Apr;149(2):323-30. doi: 10.1016/s0021-9150(99)00342-1. Atherosclerosis. 2000. PMID: 10729382

7

Stimulation of activin A expression in rat aortic smooth muscle cells by thrombin and angiotensin II correlates with neointimal formation in vivo.

Pawlowski JE, Taylor DS, Valentine M, Hail ME, Ferrer P, Kowala MC, Molloy CJ. Pawlowski JE, et al. J Clin Invest. 1997 Aug 1;100(3):639-48. doi: 10.1172/JCI119575. J Clin Invest. 1997. PMID: 9239411 Free PMC article.

8

Enhanced reduction of atherosclerosis in hamsters treated with pravastatin and captopril: ACE in atheromas provides cellular targets for captopril.

Kowala MC, Valentine M, Recce R, Beyer S, Goller N, Durham S, Aberg G. Kowala MC, et al. J Cardiovasc Pharmacol. 1998 Jul;32(1):29-38. doi: 10.1097/00005344-199807000-00005. J Cardiovasc Pharmacol. 1998. PMID: 9676717

9

Increased severity of glomerulonephritis in C-C chemokine receptor 2 knockout mice.

Bird JE, Giancarli MR, Kurihara T, Kowala MC, Valentine MT, Gitlitz PH, Pandya DG, French MH, Durham SK. Bird JE, et al. Among authors: valentine mt. Kidney Int. 2000 Jan;57(1):129-36. doi: 10.1046/j.1523-1755.2000.00848.x. Kidney Int. 2000. PMID: 10620194 Free article.

10

Orally active endothelin receptor antagonist BMS-182874 suppresses neointimal development in balloon-injured rat carotid arteries.

Ferrer P, Valentine M, Jenkins-West T, Weber H, Goller NL, Durham SK, Molloy CJ, Moreland S. Ferrer P, et al. J Cardiovasc Pharmacol. 1995 Dec;26(6):908-15. doi: 10.1097/00005344-199512000-00009. J Cardiovasc Pharmacol. 1995. PMID: 8606527

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