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Oxidative Stress and Cellular Senescence Are Involved in the Aging Kidney.
Marquez-Exposito L, Tejedor-Santamaria L, Valentijn FA, Tejera-Muñoz A, Rayego-Mateos S, Marchant V, Rodrigues-Diez RR, Rubio-Soto I, Knoppert SN, Ortiz A, Ramos AM, Goldschmeding R, Ruiz-Ortega M. Marquez-Exposito L, et al. Among authors: valentijn fa. Antioxidants (Basel). 2022 Jan 31;11(2):301. doi: 10.3390/antiox11020301. Antioxidants (Basel). 2022. PMID: 35204184 Free PMC article.
Cellular senescence in the aging and diseased kidney.
Valentijn FA, Falke LL, Nguyen TQ, Goldschmeding R. Valentijn FA, et al. J Cell Commun Signal. 2018 Mar;12(1):69-82. doi: 10.1007/s12079-017-0434-2. Epub 2017 Dec 19. J Cell Commun Signal. 2018. PMID: 29260442 Free PMC article. Review.
Acute Kidney Injury is Aggravated in Aged Mice by the Exacerbation of Proinflammatory Processes.
Marquez-Exposito L, Tejedor-Santamaria L, Santos-Sanchez L, Valentijn FA, Cantero-Navarro E, Rayego-Mateos S, Rodrigues-Diez RR, Tejera-Muñoz A, Marchant V, Sanz AB, Ortiz A, Goldschmeding R, Ruiz-Ortega M. Marquez-Exposito L, et al. Among authors: valentijn fa. Front Pharmacol. 2021 Jun 22;12:662020. doi: 10.3389/fphar.2021.662020. eCollection 2021. Front Pharmacol. 2021. PMID: 34239439 Free PMC article.
Urinary KIM-1 Correlates with the Subclinical Sequelae of Tubular Damage Persisting after the Apparent Functional Recovery from Intrinsic Acute Kidney Injury.
Cuesta C, Fuentes-Calvo I, Sancho-Martinez SM, Valentijn FA, Düwel A, Hidalgo-Thomas OA, Agüeros-Blanco C, Benito-Hernández A, Ramos-Barron MA, Gómez-Alamillo C, Arias M, Nguyen TQ, Goldschmeding R, Martínez-Salgado C, López-Hernández FJ. Cuesta C, et al. Among authors: valentijn fa. Biomedicines. 2022 May 10;10(5):1106. doi: 10.3390/biomedicines10051106. Biomedicines. 2022. PMID: 35625842 Free PMC article.
Cellular communication network 2 (connective tissue growth factor) aggravates acute DNA damage and subsequent DNA damage response-senescence-fibrosis following kidney ischemia reperfusion injury.
Valentijn FA, Knoppert SN, Marquez-Exposito L, Rodrigues-Diez RR, Pissas G, Tang J, Tejedor-Santamaria L, Broekhuizen R, Samarakoon R, Eleftheriadis T, Goldschmeding R, Nguyen TQ, Ruiz-Ortega M, Falke LL. Valentijn FA, et al. Kidney Int. 2022 Dec;102(6):1305-1319. doi: 10.1016/j.kint.2022.06.030. Epub 2022 Jul 31. Kidney Int. 2022. PMID: 35921911 Free article.
Cellular senescence in kidney biopsies is associated with tubular dysfunction and predicts CKD progression in childhood cancer patients with karyomegalic interstitial nephropathy.
Knoppert SN, Keijzer-Veen MG, Valentijn FA, van den Heuvel-Eibrink MM, Lilien MR, van den Berg G, Haveman LM, Stokman MF, Janssens GO, van Kempen S, Broekhuizen R, Goldschmeding R, Nguyen TQ. Knoppert SN, et al. Among authors: valentijn fa. J Pathol. 2023 Dec;261(4):455-464. doi: 10.1002/path.6202. Epub 2023 Oct 4. J Pathol. 2023. PMID: 37792603
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