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SETD2 non genomic loss of function in advanced systemic mastocytosis is mediated by an Aurora kinase A/MDM2 axis and can be therapeutically targeted.
Mancini M, Monaldi C, De Santis S, Papayannidis C, Rondoni M, Sartor C, Bruno S, Pagano L, Criscuolo M, Zanotti R, Bonifacio M, Tosi P, Arock M, Valent P, Cavo M, Soverini S. Mancini M, et al. Among authors: valent p. Biomark Res. 2023 Mar 10;11(1):29. doi: 10.1186/s40364-023-00468-7. Biomark Res. 2023. PMID: 36894973 Free PMC article.
Diagnosis and treatment of systemic mastocytosis: state of the art.
Valent P, Akin C, Sperr WR, Horny HP, Arock M, Lechner K, Bennett JM, Metcalfe DD. Valent P, et al. Br J Haematol. 2003 Sep;122(5):695-717. doi: 10.1046/j.1365-2141.2003.04575.x. Br J Haematol. 2003. PMID: 12930381 Free article. Review. No abstract available.
Mastocytosis: pathology, genetics, and current options for therapy.
Valent P, Akin C, Sperr WR, Mayerhofer M, Födinger M, Fritsche-Polanz R, Sotlar K, Escribano L, Arock M, Horny HP, Metcalfe DD. Valent P, et al. Leuk Lymphoma. 2005 Jan;46(1):35-48. doi: 10.1080/10428190400010775. Leuk Lymphoma. 2005. PMID: 15621779 Review.
The European Competence Network on Mastocytosis (ECNM).
Valent P, Arock M, Bischoff SC, Bühring HJ, Brockow K, Escribano L, Födinger M, Grabbe J, Hartmann K, Henz BM, Horny HP, Kluin-Nelemans HC, Lima M, Marone G, Orfao A, Parwaresch RM, Sillaber C, Sotlar K, Sperr WR, Triggiani M, Van Doormaal JJ, Wolff K, Zuberbier T. Valent P, et al. Wien Klin Wochenschr. 2004 Oct 30;116(19-20):647-51. doi: 10.1007/s00508-004-0253-3. Wien Klin Wochenschr. 2004. PMID: 15941072
942 results