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A Recombinant Chimeric Protein-Based Vaccine Containing T-Cell Epitopes from Amastigote Proteins and Combined with Distinct Adjuvants, Induces Immunogenicity and Protection against Leishmania infantum Infection.
Lage DP, Vale DL, Linhares FP, Freitas CS, Machado AS, Cardoso JMO, de Oliveira D, Galvani NC, de Oliveira MP, Oliveira-da-Silva JA, Ramos FF, Tavares GSV, Ludolf F, Bandeira RS, Pereira IAG, Chávez-Fumagalli MA, Roatt BM, Machado-de-Ávila RA, Christodoulides M, Coelho EAF, Martins VT. Lage DP, et al. Among authors: vale dl. Vaccines (Basel). 2022 Jul 19;10(7):1146. doi: 10.3390/vaccines10071146. Vaccines (Basel). 2022. PMID: 35891310 Free PMC article.
A vaccine composed of a hypothetical protein and the eukaryotic initiation factor 5a from Leishmania braziliensis cross-protection against Leishmania amazonensis infection.
Duarte MC, Lage DP, Martins VT, Costa LE, Carvalho AMRS, Ludolf F, Santos TTO, Vale DL, Roatt BM, Menezes-Souza D, Fernandes AP, Tavares CAP, Coelho EAF. Duarte MC, et al. Among authors: vale dl. Immunobiology. 2017 Feb;222(2):251-260. doi: 10.1016/j.imbio.2016.09.015. Epub 2016 Sep 28. Immunobiology. 2017. PMID: 27693018
In vivo antileishmanial efficacy of a naphthoquinone derivate incorporated into a Pluronic® F127-based polymeric micelle system against Leishmania amazonensis infection.
Mendonça DVC, Tavares GSV, Lage DP, Soyer TG, Carvalho LM, Dias DS, Ribeiro PAF, Ottoni FM, Antinarelli LMR, Vale DL, Ludolf F, Duarte MC, Coimbra ES, Chávez-Fumagalli MA, Roatt BM, Menezes-Souza D, Barichello JM, Alves RJ, Coelho EAF. Mendonça DVC, et al. Among authors: vale dl. Biomed Pharmacother. 2019 Jan;109:779-787. doi: 10.1016/j.biopha.2018.10.143. Epub 2018 Nov 5. Biomed Pharmacother. 2019. PMID: 30551531 Free article.
Screening diagnostic candidates from Leishmania infantum proteins for human visceral leishmaniasis using an immunoproteomics approach.
Lage DP, Ludolf F, Silveira PC, Machado AS, Ramos FF, Dias DS, Ribeiro PAF, Costa LE, Vale DL, Tavares GSV, Martins VT, Chávez-Fumagalli MA, Caligiorne RB, Chaves AT, Gonçalves DU, Rocha MOC, Duarte MC, Coelho EAF. Lage DP, et al. Among authors: vale dl. Parasitology. 2019 Sep;146(11):1467-1476. doi: 10.1017/S0031182019000714. Epub 2019 Jun 13. Parasitology. 2019. PMID: 31142384
Diagnostic evaluation of the amastin protein from Leishmania infantum in canine and human visceral leishmaniasis and immunogenicity in human cells derived from patients and healthy controls.
Vale DL, Dias DS, Machado AS, Ribeiro PAF, Lage DP, Costa LE, Steiner BT, Tavares GSV, Ramos FF, Martínez-Rodrigo A, Chávez-Fumagalli MA, Caligiorne RB, de Magalhães-Soares DF, Silveira JAG, Machado-de-Ávila RA, Teixeira AL, Coelho EAF. Vale DL, et al. Diagn Microbiol Infect Dis. 2019 Oct;95(2):134-143. doi: 10.1016/j.diagmicrobio.2019.04.015. Epub 2019 May 6. Diagn Microbiol Infect Dis. 2019. PMID: 31155395
Leishmania infantum amastin protein incorporated in distinct adjuvant systems induces protection against visceral leishmaniasis.
Ribeiro PAF, Vale DL, Dias DS, Lage DP, Mendonça DVC, Ramos FF, Carvalho LM, Carvalho AMRS, Steiner BT, Roque MC, Oliveira-da-Silva JA, Oliveira JS, Tavares GSV, Galvani NC, Martins VT, Chávez-Fumagalli MA, Roatt BM, Moreira RLF, Menezes-Souza D, Oliveira MC, Machado-de-Ávila RA, Teixeira AL, Coelho EAF. Ribeiro PAF, et al. Among authors: vale dl. Cytokine. 2020 May;129:155031. doi: 10.1016/j.cyto.2020.155031. Epub 2020 Feb 12. Cytokine. 2020. PMID: 32062145
Evaluation of the protective efficacy of a Leishmania protein associated with distinct adjuvants against visceral leishmaniasis and in vitro immunogenicity in human cells.
Ribeiro PAF, Dias DS, Lage DP, Mendonça DVC, Vale DL, Ramos FF, Carvalho LM, Carvalho AMRS, Steiner BT, Roque MC, Oliveira-da-Silva JA, Oliveira JS, Tavares GSV, Martins VT, Chávez-Fumagalli MA, Roatt BM, Moreira RLF, Menezes-Souza D, Duarte MC, Oliveira MC, Machado-de-Ávila RA, Teixeira AL, Coelho EAF. Ribeiro PAF, et al. Among authors: vale dl. Parasitol Res. 2020 Aug;119(8):2609-2622. doi: 10.1007/s00436-020-06752-x. Epub 2020 Jun 13. Parasitol Res. 2020. PMID: 32535734
Serodiagnosis of canine leishmaniasis using a novel recombinant chimeric protein constructed with distinct B-cell epitopes from antigenic Leishmania infantum proteins.
Vale DL, Lage DP, Machado AS, Freitas CS, de Oliveira D, Galvani NC, Fernandes BB, Luiz GP, Oliveira JS, Oliveira-da-Silva JA, Ramos FF, Santos TTO, Siqueira WF, Alves LA, Chávez-Fumagalli MA, de Magalhães-Soares DF, Silveira JAG, Bueno LL, Fujiwara RT, Machado-de-Ávila RA, Martins VT, Coelho EAF. Vale DL, et al. Vet Parasitol. 2021 Aug;296:109513. doi: 10.1016/j.vetpar.2021.109513. Epub 2021 Jul 1. Vet Parasitol. 2021. PMID: 34225189
Potential of recombinant LiHyQ, a novel Leishmania infantum protein, for the diagnosis of canine visceral leishmaniasis and as a diagnostic and prognostic marker for human leishmaniasis and human immunodeficiency virus co-infection: A preliminary study.
Santos TTO, Ramos FF, Gonçalves IAP, Tavares GSV, Ludolf F, Bandeira RS, Silva AM, Oliveira-da-Silva JA, Reis TAR, Machado AS, Lage DP, Freitas CS, Vale DL, Martins VT, Alves LA, Guimarães NS, Chaves AT, Chávez-Fumagalli MA, Cota GF, Silveira JAG, Tupinambás U, Gonçalves DU, Christodoulides M, Coelho EAF. Santos TTO, et al. Among authors: vale dl. Acta Trop. 2021 Dec;224:106126. doi: 10.1016/j.actatropica.2021.106126. Epub 2021 Sep 16. Acta Trop. 2021. PMID: 34537185
37 results