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Constitutive activation of the PI3K-Akt-mTORC1 pathway sustains the m.3243 A > G mtDNA mutation.
Nat Commun. 2021 Nov 4;12(1):6409. doi: 10.1038/s41467-021-26746-2.
Nat Commun. 2021.
PMID: 34737295
Free PMC article.
Rewiring cell signalling pathways in pathogenic mtDNA mutations.
Chung CY, Valdebenito GE, Chacko AR, Duchen MR.
Chung CY, et al. Among authors: valdebenito ge.
Trends Cell Biol. 2022 May;32(5):391-405. doi: 10.1016/j.tcb.2021.10.005. Epub 2021 Nov 23.
Trends Cell Biol. 2022.
PMID: 34836781
Free article.
Review.
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Monitoring Mitochondrial Membrane Potential in Live Cells Using Time-Lapse Fluorescence Imaging.
Valdebenito GE, Duchen MR.
Valdebenito GE, et al.
Methods Mol Biol. 2022;2497:319-324. doi: 10.1007/978-1-0716-2309-1_22.
Methods Mol Biol. 2022.
PMID: 35771453
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The mitochondrial ATP synthase as an ATP consumer-a surprising therapeutic target.
Valdebenito GE, Chacko AR, Duchen MR.
Valdebenito GE, et al.
EMBO J. 2023 May 15;42(10):e114141. doi: 10.15252/embj.2023114141. Epub 2023 Apr 6.
EMBO J. 2023.
PMID: 37021792
Free PMC article.
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