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Drag-and-drop genome insertion of large sequences without double-strand DNA cleavage using CRISPR-directed integrases.
Yarnall MTN, Ioannidi EI, Schmitt-Ulms C, Krajeski RN, Lim J, Villiger L, Zhou W, Jiang K, Garushyants SK, Roberts N, Zhang L, Vakulskas CA, Walker JA 2nd, Kadina AP, Zepeda AE, Holden K, Ma H, Xie J, Gao G, Foquet L, Bial G, Donnelly SK, Miyata Y, Radiloff DR, Henderson JM, Ujita A, Abudayyeh OO, Gootenberg JS. Yarnall MTN, et al. Among authors: vakulskas ca. Nat Biotechnol. 2023 Apr;41(4):500-512. doi: 10.1038/s41587-022-01527-4. Epub 2022 Nov 24. Nat Biotechnol. 2023. PMID: 36424489 Free PMC article.
Circuitry linking the Csr and stringent response global regulatory systems.
Edwards AN, Patterson-Fortin LM, Vakulskas CA, Mercante JW, Potrykus K, Vinella D, Camacho MI, Fields JA, Thompson SA, Georgellis D, Cashel M, Babitzke P, Romeo T. Edwards AN, et al. Among authors: vakulskas ca. Mol Microbiol. 2011 Jun;80(6):1561-80. doi: 10.1111/j.1365-2958.2011.07663.x. Epub 2011 May 5. Mol Microbiol. 2011. PMID: 21488981 Free PMC article.
Dual posttranscriptional regulation via a cofactor-responsive mRNA leader.
Patterson-Fortin LM, Vakulskas CA, Yakhnin H, Babitzke P, Romeo T. Patterson-Fortin LM, et al. Among authors: vakulskas ca. J Mol Biol. 2013 Oct 9;425(19):3662-77. doi: 10.1016/j.jmb.2012.12.010. Epub 2012 Dec 28. J Mol Biol. 2013. PMID: 23274138 Free PMC article.
Regulation of bacterial virulence by Csr (Rsm) systems.
Vakulskas CA, Potts AH, Babitzke P, Ahmer BM, Romeo T. Vakulskas CA, et al. Microbiol Mol Biol Rev. 2015 Jun;79(2):193-224. doi: 10.1128/MMBR.00052-14. Microbiol Mol Biol Rev. 2015. PMID: 25833324 Free PMC article. Review.
40 results