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Adenoviral expression of human lecithin-cholesterol acyltransferase in nonhuman primates leads to an antiatherogenic lipoprotein phenotype by increasing high-density lipoprotein and lowering low-density lipoprotein.
Amar MJ, Shamburek RD, Vaisman B, Knapper CL, Foger B, Hoyt RF Jr, Santamarina-Fojo S, Brewer HB Jr, Remaley AT. Amar MJ, et al. Among authors: vaisman b. Metabolism. 2009 Apr;58(4):568-75. doi: 10.1016/j.metabol.2008.11.019. Metabolism. 2009. PMID: 19303980 Free PMC article.
High pre-beta1 HDL concentrations and low lecithin: cholesterol acyltransferase activities are strong positive risk markers for ischemic heart disease and independent of HDL-cholesterol.
Sethi AA, Sampson M, Warnick R, Muniz N, Vaisman B, Nordestgaard BG, Tybjaerg-Hansen A, Remaley AT. Sethi AA, et al. Among authors: vaisman b. Clin Chem. 2010 Jul;56(7):1128-37. doi: 10.1373/clinchem.2009.139931. Epub 2010 May 28. Clin Chem. 2010. PMID: 20511449 Free PMC article.
ABCA1 overexpression in the liver of LDLr-KO mice leads to accumulation of pro-atherogenic lipoproteins and enhanced atherosclerosis.
Joyce CW, Wagner EM, Basso F, Amar MJ, Freeman LA, Shamburek RD, Knapper CL, Syed J, Wu J, Vaisman BL, Fruchart-Najib J, Billings EM, Paigen B, Remaley AT, Santamarina-Fojo S, Brewer HB Jr. Joyce CW, et al. Among authors: vaisman bl. J Biol Chem. 2006 Nov 3;281(44):33053-65. doi: 10.1074/jbc.M604526200. Epub 2006 Aug 23. J Biol Chem. 2006. PMID: 16928680 Free article.
Lecithin:Cholesterol Acyltransferase Activation by Sulfhydryl-Reactive Small Molecules: Role of Cysteine-31.
Freeman LA, Demosky SJ Jr, Konaklieva M, Kuskovsky R, Aponte A, Ossoli AF, Gordon SM, Koby RF, Manthei KA, Shen M, Vaisman BL, Shamburek RD, Jadhav A, Calabresi L, Gucek M, Tesmer JJG, Levine RL, Remaley AT. Freeman LA, et al. Among authors: vaisman bl. J Pharmacol Exp Ther. 2017 Aug;362(2):306-318. doi: 10.1124/jpet.117.240457. Epub 2017 Jun 2. J Pharmacol Exp Ther. 2017. PMID: 28576974 Free PMC article.
101 results