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Keeping Cell Death Alive: An Introduction into the French Cell Death Research Network.
Ichim G, Gibert B, Adriouch S, Brenner C, Davoust N, Desagher S, Devos D, Dokudovskaya S, Dubrez L, Estaquier J, Gillet G, Guénal I, Juin PP, Kroemer G, Legembre P, Levayer R, Manon S, Mehlen P, Meurette O, Micheau O, Mignotte B, Nguyen-Khac F, Popgeorgiev N, Poyet JL, Priault M, Ricci JE, Riquet FB, Susin SA, Suzanne M, Vacher P, Walter L, Mollereau B. Ichim G, et al. Among authors: vacher p. Biomolecules. 2022 Jun 28;12(7):901. doi: 10.3390/biom12070901. Biomolecules. 2022. PMID: 35883457 Free PMC article. Review.
Does calcium contribute to the CD95 signaling pathway?
Vacher P, Khadra N, Vacher AM, Charles E, Bresson-Bepoldin L, Legembre P. Vacher P, et al. Among authors: vacher am. Anticancer Drugs. 2011 Jul;22(6):481-7. doi: 10.1097/CAD.0b013e32834433ea. Anticancer Drugs. 2011. PMID: 21317766 Review.
TRAIL receptor gene editing unveils TRAIL-R1 as a master player of apoptosis induced by TRAIL and ER stress.
Dufour F, Rattier T, Constantinescu AA, Zischler L, Morlé A, Ben Mabrouk H, Humblin E, Jacquemin G, Szegezdi E, Delacote F, Marrakchi N, Guichard G, Pellat-Deceunynck C, Vacher P, Legembre P, Garrido C, Micheau O. Dufour F, et al. Among authors: vacher p. Oncotarget. 2017 Feb 7;8(6):9974-9985. doi: 10.18632/oncotarget.14285. Oncotarget. 2017. PMID: 28039489 Free PMC article.
CD95/Fas and metastatic disease: What does not kill you makes you stronger.
Guégan JP, Ginestier C, Charafe-Jauffret E, Ducret T, Quignard JF, Vacher P, Legembre P. Guégan JP, et al. Among authors: vacher p. Semin Cancer Biol. 2020 Feb;60:121-131. doi: 10.1016/j.semcancer.2019.06.004. Epub 2019 Jun 6. Semin Cancer Biol. 2020. PMID: 31176682 Free article. Review.
The apoptotic members CD95, BclxL, and Bcl-2 cooperate to promote cell migration by inducing Ca(2+) flux from the endoplasmic reticulum to mitochondria.
Fouqué A, Lepvrier E, Debure L, Gouriou Y, Malleter M, Delcroix V, Ovize M, Ducret T, Li C, Hammadi M, Vacher P, Legembre P. Fouqué A, et al. Among authors: vacher p. Cell Death Differ. 2016 Oct;23(10):1702-16. doi: 10.1038/cdd.2016.61. Epub 2016 Jul 1. Cell Death Differ. 2016. PMID: 27367565 Free PMC article.
CD95 triggers Orai1-mediated localized Ca2+ entry, regulates recruitment of protein kinase C (PKC) β2, and prevents death-inducing signaling complex formation.
Khadra N, Bresson-Bepoldin L, Penna A, Chaigne-Delalande B, Ségui B, Levade T, Vacher AM, Reiffers J, Ducret T, Moreau JF, Cahalan MD, Vacher P, Legembre P. Khadra N, et al. Among authors: vacher p, vacher am. Proc Natl Acad Sci U S A. 2011 Nov 22;108(47):19072-7. doi: 10.1073/pnas.1116946108. Epub 2011 Nov 7. Proc Natl Acad Sci U S A. 2011. PMID: 22065776 Free PMC article.
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